在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human 26S proteasome non-ATPase regulatory subunit 11 (PSMD11)

  • 中文名稱:
    Recombinant Human 26S proteasome non-ATPase regulatory subunit 11 (PSMD11)
  • 貨號:
    CSB-EP018901HU
  • 規格:
    ¥1536
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    PSMD11
  • Uniprot No.:
  • 別名:
    26S proteasome regulatory subunit RPN6;26S proteasome regulatory subunit S9;26S proteasome regulatory subunit p44.5
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    54.2 kDa
  • 表達區域:
    2-422aa
  • 氨基酸序列
    AAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
  • 基因功能參考文獻:
    1. human embryonic stem cells (hESCs) exhibit high proteasome activity that is correlated with increased levels of the 19S proteasome subunit PSMD11 (known as RPN-6 in Caenorhabditis elegans) and a corresponding increased assembly of the 26S/30S proteasome PMID: 22972301
    2. AMP-activated protein kinase is able to interact physically with this subunit and modify its phosphorylation status. PMID: 19616115
    3. interaction with ubiquitinated NF-kappaB2/p100 PMID: 12185077
  • 亞細胞定位:
    Nucleus. Cytoplasm, cytosol.
  • 蛋白家族:
    Proteasome subunit S9 family
  • 組織特異性:
    Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate.
  • 數據庫鏈接:

    HGNC: 9556

    OMIM: 604449

    KEGG: hsa:5717

    STRING: 9606.ENSP00000261712

    UniGene: Hs.443379



主站蜘蛛池模板: 日韩内射激情视频在线播放免费| 国产交换配乱婬视频| 四虎成人精品在永久免费| 国产97在线 | 免费| 日本在线看片免费人成视频| 日日噜噜大屁股熟妇| 久久久橹橹橹久久久久| 日韩人妻一区二区三区蜜桃视频| 无码人妻一区二区三区免费| 国产av老师丝袜美腿丝袜| 精品无码国产日韩制服丝袜| 精品亚洲成a人在线观看| 国精产品一二三区传媒公司| 国产熟女精品视频大全| 中文字幕精品亚洲无线码vr| 欧美人禽zozo动人物杂交| 亚洲午夜成人片| 久久久精品国产sm最大网站| 日韩插啊免费视频在线观看| 国产传媒麻豆剧精品av| 国产亚洲精品在av| 色一情一乱一伦麻豆| 久久亚洲精品中文字幕| 国产乱码日产精品bd| 欧美精品黑人粗大破除| 国精产品一区一区三区免费视频| 性做久久久久久| 亚洲中文字幕无码久久2020| 人妻丰满熟妇av无码区动漫| 久久人人爽人人爽人人片av不| 国产乱子伦视频一区二区三区| 少妇激情av一区二区三区| 欧美精品一产区二产区| 国产伦精品免编号公布| 日本人妻伦在线中文字幕| 国产suv精二区| 国产精品亚洲色婷婷99久久精品| 无码gogo大胆啪啪艺术| 久久精品国产欧美日韩99热| 丰满少妇在线观看网站| 少妇无码一区二区三区|