在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human 26S protease regulatory subunit 4 (PSMC1)

  • 中文名稱:
    人PSMC1重組蛋白
  • 貨號:
    CSB-YP018888HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PSMC1重組蛋白
  • 貨號:
    CSB-EP018888HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PSMC1重組蛋白
  • 貨號:
    CSB-EP018888HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PSMC1重組蛋白
  • 貨號:
    CSB-BP018888HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PSMC1重組蛋白
  • 貨號:
    CSB-MP018888HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PSMC1
  • Uniprot No.:
  • 別名:
    26S protease regulatory subunit 4; 26S proteasome AAA-ATPase subunit RPT2; MGC24583; MGC8541; P26s4; p56; protease 26S, subunit 4; Proteasome (prosome macropain) 26S subunit ATPase 1; Proteasome 26S ATPase subunit 1; Proteasome 26S subunit ATPase 1; PRS4_HUMAN; PSMC 1; Psmc1; S4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-440
  • 氨基酸序列
    GQSQSGGHG PGGGKKDDKD KKKKYEPPVP TRVGKKKKKT KGPDAASKLP LVTPHTQCRL KLLKLERIKD YLLMEEEFIR NQEQMKPLEE KQEEERSKVD DLRGTPMSVG TLEEIIDDNH AIVSTSVGSE HYVSILSFVD KDLLEPGCSV LLNHKVHAVI GVLMDDTDPL VTVMKVEKAP QETYADIGGL DNQIQEIKES VELPLTHPEY YEEMGIKPPK GVILYGPPGT GKTLLAKAVA NQTSATFLRV VGSELIQKYL GDGPKLVREL FRVAEEHAPS IVFIDEIDAI GTKRYDSNSG GEREIQRTML ELLNQLDGFD SRGDVKVIMA TNRIETLDPA LIRPGRIDRK IEFPLPDEKT KKRIFQIHTS RMTLADDVTL DDLIMAKDDL SGADIKAICT EAGLMALRER RMKVTNEDFK KSKENVLYKK QEGTPEGLYL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC1 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
  • 基因功能參考文獻:
    1. P26s4 Associates with the C-Terminal Region of TOPORS. PMID: 26872363
    2. Our results suggest that there is no association between variations or haplotypes in the PSMC1 gene and Parkinson's disease PMID: 22948515
    3. Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity PMID: 20424172
    4. Hepatocytes dying because of inhibition of proteasome function produce massive quantities of the proinflammatory chemokine IL-8, possibly resulting in neutrophil infiltration, increased inflammation, and liver injury. PMID: 14578856
    5. Psmc1 conditional knock-out mice demonstrate that 26S proteasomal dysfunction is sufficient to trigger neurodegenerative disease. PMID: 18701681

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Membrane; Lipid-anchor.
  • 蛋白家族:
    AAA ATPase family
  • 數據庫鏈接:

    HGNC: 9547

    OMIM: 602706

    KEGG: hsa:5700

    STRING: 9606.ENSP00000261303

    UniGene: Hs.356654



主站蜘蛛池模板: 久久国内精品自在自线| 青青久在线视频免费观看| 中文在线а√天堂| 国产98色在线 | 国| av区无码字幕中文色| 综合图区亚洲欧美另类图片| 最爽free性欧美人妖| 老司机无码精品a| 西西艺术人像摄影| 免费毛儿一区二区十八岁| 欧美又大粗又爽又黄大片视频| 在线欧美日韩制服国产| 亚洲国产老鸭窝一区二区三区| 久久99精品九九九久久婷婷| 非洲人与性动交ccoo| 正在播放东北夫妻内射| 精品国产免费人成电影在线看| 国产人妻久久精品二区三区老狼| 亚洲精品www久久久久久| 亚洲mv国产mv在线mv综合试看| 最大胆裸体人体牲交免费| 国产丝袜一区视频在线观看| 亚洲精品久久久久中文第一幕| 国产欧美另类精品久久久| 国产福利免费视频不卡| 久久精品免费一区二区| 粉嫩被粗大进进出出视频| 国产大量精品视频网站| 亚洲美女又黄又爽在线观看| 成人精品视频一区二区三区| 青草av久久一区二区三区| 欧美综合在线激情专区| 髙清国产性猛交xxxand| 亚洲精品国产精品无码国模| 无码人妻少妇精品无码专区漫画| 国产激情з∠视频一区二区 | 亚洲s码欧洲m码国产av| 中文字幕无码精品三级在线电影 | 天堂中文在线资源| 天天躁久久躁日日躁| 男女18禁啪啪无遮挡|