在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ADI1)

  • 中文名稱:
    Recombinant Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(ADI1)
  • 貨號:
    CSB-YP861145HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(ADI1)
  • 貨號:
    CSB-EP861145HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(ADI1)
  • 貨號:
    CSB-EP861145HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(ADI1)
  • 貨號:
    CSB-BP861145HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase(ADI1)
  • 貨號:
    CSB-MP861145HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ADI1
  • Uniprot No.:
  • 別名:
    1 2 dihydroxy 3 keto 5 methylthiopentene dioxygenase; 1; 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Aci reductone dioxygenase; Acireductone dioxygenase (Fe(2+) requiring); Acireductone dioxygenase (Ni(2+) requiring); Acireductone dioxygenase (Ni(2+)-requiring); Acireductone dioxygenase 1; ADI 1; Adi1; ADI1; APL1; ARD; EC 1.13.; Fe ARD; FLJ10913; HMFT1638; Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; MT1 MMP cytoplasmic tail binding protein 1; MTCBP 1; MTCBP-1; MTCBP1; MTND_HUMAN; Ni-ARD; SIPL; Submergence induced protein 2; Submergence induced protein 2 homolog; Submergence induced protein like factor; Submergence-induced protein 2 homolog
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-179
  • 氨基酸序列
    MVQAWYMDDA PGDPRQPHRP DPGRPVGLEQ LRRLGVLYWK LDADKYENDP ELEKIRRERN YSWMDIITIC KDKLPNYEEK IKMFYEEHLH LDDEIRYILD GSGYFDVRDK EDQWIRIFME KGDMVTLPAG IYHRFTVDEK NYTKAMRLFV GEPVWTAYNR PADHFEARGQ YVKFLAQTA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
  • 基因功能參考文獻:
    1. High ADI1 expression is associated with malignant glioma. PMID: 30066900
    2. The thermal stability of the HsARD isozymes is a function of the metal ion identity, with Ni2+-bound HsARD being the most stable followed by Co2+ and Fe2+, and Mn2+-bound HsARD being the least stable. PMID: 28062648
    3. In summary, clinical and cell-based experiments suggested that physical interaction between MT1-MMP and ADI1 led to suppression of hepatitis C virus infection. This inhibitory effect could be reversed by ADI1 overexpression. PMID: 26537061
    4. Data elucidate a new role for MTCBP-1 regulating the intracellular function of MT1-MMP-mediated autophagy. Their inverse expression correlation with brain tumor grades could also contribute to the decreased autophagic index observed in high-grade tumors. PMID: 25640948
    5. MTCBP-1 is a new member of the Cupin superfamily with a role as an invasion suppressor down-regulated in tumors PMID: 14718544
    6. nucleo-cytoplasmic transport of hADI1 is regulated by a non-canonical nuclear export signal (NES) located in the N-terminal region of hADI1. PMID: 17212658
    7. ADI1 may check prostate cancer progression through apoptosis by an activity that does not require metal binding. PMID: 17786183
    8. 293-ADI1-CD81 cells are permissive for serum-derived HCV infection. PMID: 19626614

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14.
  • 蛋白家族:
    Acireductone dioxygenase (ARD) family
  • 組織特異性:
    Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney.
  • 數據庫鏈接:

    HGNC: 30576

    OMIM: 613400

    KEGG: hsa:55256

    STRING: 9606.ENSP00000333666

    UniGene: Hs.502773



主站蜘蛛池模板: 麻豆精品国产熟妇aⅴ一区| 日夜啪啪一区二区三区| 亚洲中文字幕无码av正片| 亚洲人成77777在线播放网站不卡 国产 | 欧洲野花视频天堂视频p 亚洲aⅴ天堂av天堂无码 | 中文字幕人成无码人妻| 国产亚洲精品久久久久久小说| 国内精品乱码卡一卡2卡三卡新区| 亚洲综合激情七月婷婷| 婷婷色婷婷开心五月四房播播| 日韩精品人妻系列无码专区| 狼群社区www中文视频| 蜜臀视频一区二区在线播放| 国产午夜精品一区二区三区| 亚洲乱亚洲乱妇小说网| 超清无码av最大网站| 久久精品道一区二区三区| 欧美人与性动交α欧美精品| 少妇三级全黄| 亚洲午夜无码极品久久| 日韩精品少妇无码受不了| 色欲香天天天综合网站| 无码一区二区波多野结衣播放搜索 | 性中国妓女毛茸茸视频| 久久久久蜜桃精品成人片公司| 精品无码一区二区三区在线| 国产亚洲日韩在线播放更多| 午夜肉伦伦影院| 国产亚洲精品成人aa片| 中文在线а天堂中文在线新版| 亚洲精品色无码av试看| 国产农村乱辈无码| 亚洲 欧美 变态 另类 综合 | 少妇人妻av毛片在线看| 欧美乱强伦xxxxx高潮| 大帝a∨无码视频在线播放| 久久人妻av一区二区软件| 又色又污又爽又黄的网站| 99久久国产亚洲高清观看| 女女女女女裸体处开bbb| 看成年女人午夜毛片免费| 久久亚洲精品中文字幕一区|