在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Horse Interleukin-10 (IL10)

  • 中文名稱:
    Recombinant Horse Interleukin-10(IL10)
  • 貨號:
    CSB-YP634667HO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Horse Interleukin-10(IL10)
  • 貨號:
    CSB-EP634667HO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Horse Interleukin-10(IL10)
  • 貨號:
    CSB-EP634667HO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Horse Interleukin-10(IL10)
  • 貨號:
    CSB-BP634667HO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Horse Interleukin-10(IL10)
  • 貨號:
    CSB-MP634667HO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    IL10Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF
  • 種屬:
    Equus caballus (Horse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    19-178
  • 氨基酸序列
    SR DRGTQSENSC THFPTSLPHM LHELRAAFSR VKTFFQMKDQ LDNMLLNGSL LEDFKGYLGC QALSEMIQFY LEEVMPQAEN HGPDIKEHVN SLGEKLKTLR VRLRRCHRFL PCENKSKAVE QVKSAFSKLQ EKGVYKAMSE FDIFINYIEA YMTTKMKN
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha. Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation. In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling.
  • 基因功能參考文獻(xiàn):
    1. The ability of an EHV-1 isolate to down-regulate IL-10 production might contribute to increased local inflammation and a higher risk for neurological manifestation of the disease after infection with Ab4. PMID: 21764140
    2. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 biased, interferon-gamma production is qualitatively similar to adult horses, and regulatory IL-10 production by T cells is mature. PMID: 20374696
    3. serum IL-6:IL-10 ratio is likely to provide a valuable prognosticator for neonatal septicemia PMID: 19501415
    4. The effect of clenbuterol on cytokine metabolism in the peripheral white blood cells in those horses with small airway diseases that have been exposed to lipopolysaccharides is reported. PMID: 17139543
    5. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6, IL-10 and TNF-alpha, in horses with recurrent airway obstruction during exacerbation and in remission is reported. PMID: 18294392

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    IL-10 family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 国产亚洲精品自在久久vr| 开心婷婷五月激情综合社区| 377人体粉嫩噜噜噜| 男人靠女人免费视频网站| 无码熟妇人妻av在线影片| 国产精久久一区二区三区| 国产在线观看黄av免费| 伊人亚洲综合影院首页| 久久亚洲精品中文字幕一区| 熟女人妻高清一区二区三区| 无码喷水一区二区浪潮av| 日产精品久久久久久久性色| 久久精品中文字幕无码绿巨人| 好男人社区www在线官网| 七七久久成人影院网站| 久久久亚洲欧洲日产国码二区| 欧美激欧美啪啪片| 无码人妻精品一区二区三区9厂| 久久99国产精品成人| 久久久av男人的天堂| 18禁无遮挡羞羞污污污污网站| 国产精品久久久久久不卡盗摄| 国产又粗又大又黄| 精品人妻无码专区在线无广告视频| 国产三级在线观看免费| 色777狠狠狠综合| 麻豆国产av尤物网站尤物| 国产成人精品亚洲日本在线| 人妻无码一区二区三区 tv| 日本高清一二三不卡区| 国产乱子伦一区二区三区视频播放 | 农村乱人伦一区二区| 丰满爆乳一区二区三区| 婷婷色中文字幕综合在线| 无码人妻精品一区二区三区免费| 亚洲国产精品无码专区影院| 精品国产乱码久久久久久口爆| 四虎成人精品国产永久免费无码| 中文字幕三级人妻无码视频| 国产精品爽爽ⅴa在线观看| 伊人久久大香线蕉av五月天宝贝|