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  4. Recombinant Horse Calcium-activated chloride channel regulator 1 (CLCA1), partial

Recombinant Horse Calcium-activated chloride channel regulator 1 (CLCA1), partial

  • 中文名稱：
    Recombinant Horse Calcium-activated chloride channel regulator 1(CLCA1) ,partial
  • 貨號：
    CSB-YP647214HO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Horse Calcium-activated chloride channel regulator 1(CLCA1) ,partial
  • 貨號：
    CSB-EP647214HO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Horse Calcium-activated chloride channel regulator 1(CLCA1) ,partial
  • 貨號：
    CSB-EP647214HO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Horse Calcium-activated chloride channel regulator 1(CLCA1) ,partial
  • 貨號：
    CSB-BP647214HO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Horse Calcium-activated chloride channel regulator 1(CLCA1) ,partial
  • 貨號：
    CSB-MP647214HO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CLCA1
  • Uniprot No.：
  • 別名：
    CLCA1Calcium-activated chloride channel regulator 1; EC 3.4.-.-; Calcium-activated chloride channel family member 1; eCLCA1
  • 種屬：
    Equus caballus (Horse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.
  • 基因功能參考文獻：
    1. These data implicate CLCA1 in the expression of eqMUC5AC in horses; and suggest regulation by CLCA1 and epidermal growth factor receptor between horses with recurrent airway obstruction and those with milder degrees of inflammation. PMID: 20095232
    2. In this study, eCLCA1 protein and mRNA expression were quantified in airway goblet cells of horses with RAO and controls using immunohistochemistry and laser microdissection followed by RT-PCR, respectively. PMID: 18039903
  • 亞細胞定位：
    Secreted, extracellular space.
  • 蛋白家族：
    CLCR family
  • 組織特異性：
    Expressed in mucin-producing cells in the respiratory and intestinal tracts, cutaneous sweat glands, and renal mucous glands (at protein level). Strong overexpression in the airways of horses with recurrent airway obstruction (at protein level).
  • 數據庫鏈接：


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