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  4. Recombinant Glutamate receptor 2 (glr-2), partial

Recombinant Glutamate receptor 2 (glr-2), partial

  • 中文名稱：
    秀麗隱桿線蟲glr-2重組蛋白
  • 貨號：
    CSB-YP608850CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲glr-2重組蛋白
  • 貨號：
    CSB-EP608850CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲glr-2重組蛋白
  • 貨號：
    CSB-EP608850CXY-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲glr-2重組蛋白
  • 貨號：
    CSB-BP608850CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲glr-2重組蛋白
  • 貨號：
    CSB-MP608850CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    glr-2
  • Uniprot No.：
  • 別名：
    glr-2; B0280.12/K04G7.2Glutamate receptor 2
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of glutamate are mediated by a variety of receptors that are named according to their selective agonists. Required for response to mechanical and osmotic stimuli.
  • 基因功能參考文獻：
    1. unfolded protein response signaling is a critical step in neural function that is needed for GLR-1, GLR-2, and GLR-5 assembly and secretion PMID: 15317844
    2. An arginine residue was introduced into the pore loop of glutamate receptor subunit, GLR-2. Synaptically activated GLR-2R-containing iGluR channels appear to trigger inappropriate, neurotoxic Ca2+ release from intracellular stores. PMID: 15371514
    3. Cytosolic tail sequences and subunit interactions of GLR-1 and GLR-2 are critical for synaptic localization of glutamate receptors PMID: 15840655
    4. previously-stimulated animals later habituate to subsequent mechanostimulation more rapidly compared to animals initially reared without mechanical stimulation; MAGI-1L, GLR-1, and GLR-2 are required for this change in habituation kinetics. PMID: 19242552
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Glutamate-gated ion channel (TC 1.A.10.1) family
  • 組織特異性：
    Command interneurons of the locomotory control circuit (AIA, AIB, AVA, AVD, AVE, PVC, RIA, RIG and RIR) and motor neurons (AVG, M1, RMDD and RMDV).
  • 數(shù)據(jù)庫鏈接：

    KEGG: cel:CELE_B0280.12

    STRING: 6239.B0280.12b

    UniGene: Cel.19346



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