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  4. Recombinant Frataxin, mitochondrial (frh-1), partial

Recombinant Frataxin, mitochondrial (frh-1), partial

  • 中文名稱：
    秀麗隱桿線蟲frh-1重組蛋白
  • 貨號(hào)：
    CSB-YP880020CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲frh-1重組蛋白
  • 貨號(hào)：
    CSB-EP880020CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲frh-1重組蛋白
  • 貨號(hào)：
    CSB-EP880020CXY-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲frh-1重組蛋白
  • 貨號(hào)：
    CSB-BP880020CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲frh-1重組蛋白
  • 貨號(hào)：
    CSB-MP880020CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    frh-1
  • Uniprot No.：
  • 別名：
    frh-1; F59G1.7Frataxin; mitochondrial; Fxn; EC 1.16.3.1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 表達(dá)區(qū)域：
    -
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+). May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization.
  • 基因功能參考文獻(xiàn)：
    1. Demonstrate a causal connection between induction of autophagy and lifespan extension following reduced frataxin expression. PMID: 23247094
    2. Frataxin suppression by RNAi significantly extends lifespan in C. elegans. PMID: 15771615
    3. The genomic structure of frh-1, the development of an RNA interference model, and the interaction of frh-1 with mev-1 are reported. PMID: 16293572
    4. Study describes in detail the structure of all of the coding units within the CEOP2232 operon, coding for frataxin; it is composed of eight genes of a diverse nature, organized in a complex structure. PMID: 17174523
    5. Frataxin suppression by RNAi significantly reduces lifespan in C. elegans. PMID: 17215485

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  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    Frataxin family
  • 數(shù)據(jù)庫鏈接：

    KEGG: cel:CELE_F59G1.7

    STRING: 6239.F59G1.7.1

    UniGene: Cel.20708



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