在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Foot-and-mouth disease virus Genome polyprotein, partial

  • 中文名稱:
    Recombinant Foot-and-mouth disease virus Genome polyprotein ,partial
  • 貨號:
    CSB-YP365903FCF
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Foot-and-mouth disease virus Genome polyprotein ,partial
  • 貨號:
    CSB-EP365903FCF
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Foot-and-mouth disease virus Genome polyprotein ,partial
  • 貨號:
    CSB-EP365903FCF-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Foot-and-mouth disease virus Genome polyprotein ,partial
  • 貨號:
    CSB-BP365903FCF
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Foot-and-mouth disease virus Genome polyprotein ,partial
  • 貨號:
    CSB-MP365903FCF
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    Genome polyprotein [Cleaved into: Leader protease; Lpro; EC 3.4.22.46); Protein VP0; VP4-VP2); Protein VP4; P1A; Virion protein 4); Protein VP2; P1B; Virion protein 2); Protein VP3; P1C; Virion protein 3); Protein VP1; P1D; Virion protein 1); Protein 2A; P2A; P52); Protein 2B; P2B); Protein 2C; P2C; EC 3.6.1.15); Protein 3A; P3A); Protein 3B-1; P3B-1; Genome-linked protein VPg1); Protein 3B-2; P3B-2; Genome-linked protein VPg2); Protein 3B-3; P3B-3; Genome-linked protein VPg3); Protease 3C; EC 3.4.22.28; Picornain 3C; P3C; Protease P20B); RNA-directed RNA polymerase 3D-POL; P3D-POL; EC 2.7.7.48; P56A)]
  • 種屬:
    Foot-and-mouth disease virus (strain A5) (Aphthovirus A) (FMDV)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Autocatalytically cleaves itself from the polyprotein at the L/VP0 junction. Cleaves also the host translation initiation factors EIF4G1 and EIF4G3, in order to shutoff the capped cellular mRNA transcription. Plays a role in counteracting host innate antiviral response using diverse mechanisms. Possesses a deubiquitinase activity acting on both 'Lys'-48 and 'Lys'-63-linked polyubiquitin chains. In turn, inhibits the ubiquitination and subsequent activation of key signaling molecules of type I IFN response such as host DDX58, TBK1, TRAF3 and TRAF6. Inhibits host NF-kappa-B activity by inducing a decrease in RELA mRNA levels. Cleaves a peptide bond in the C-terminus of host ISG15, resulting in the damaging of this mofidier that can no longer be attached to target proteins. Cleaves also host G3BP1 and G3BP2 in order to inhibit cytoplasmic stress granules assembly.; Capsid protein VP4: Lies on the inner surface of the capsid shell. After binding to the host receptor, the capsid undergoes conformational changes. Capsid protein VP4 is released, capsid protein VP1 N-terminus is externalized, and together, they shape a pore in the host membrane through which the viral genome is translocated into the host cell cytoplasm. After genome has been released, the channel shrinks.; Capsid protein VP2: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP1 and VP3. The capsid is composed of 60 copies of each capsid protein organized in the form of twelve pentamers and encloses the viral positive strand RNA genome.; Capsid protein V1: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is composed of 60 copies of each capsid protein organized in the form of twelve pentamers and encloses the viral positive strand RNA genome. Mediates cell entry by attachment to an integrin receptor, usually host ITGAV/ITGB6, via a conserved arginine-glycine-aspartic acid (R-G-D) motif.; Capsid protein V3: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP0 and VP3. The capsid is composed of 60 copies of each capsid protein organized in the form of twelve pentamers and encloses the viral positive strand RNA genome.; Mediates self-processing of the polyprotein by a translational effect termed 'ribosome skipping'. Mechanistically, 2A-mediated cleavage occurs between the C-terminal glycine and the proline of the downstream protein 2B. In the case of foot-and-mouth disease virus, the 2A oligopeptide is post-translationally 'trimmed' from the C-terminus of the upstream protein 1D by 3C proteinase.; Plays an essential role in the virus replication cycle by acting as a viroporin. Creates a pore in the host reticulum endoplasmic and as a consequence releases Ca2+ in the cytoplasm of infected cell. In turn, high levels of cytoplasmic calcium may trigger membrane trafficking and transport of viral ER-associated proteins to viroplasms, sites of viral genome replication.; Associates with and induces structural rearrangements of intracellular membranes. Triggers host autophagy by interacting with host BECN1 and thereby promotes viral replication. Participates in viral replication and interacts with host DHX9. Displays RNA-binding, nucleotide binding and NTPase activities. May play a role in virion morphogenesis and viral RNA encapsidation by interacting with the capsid protein VP3.; Plays important roles in virus replication, virulence and host range.; Covalently linked to the 5'-end of both the positive-strand and negative-strand genomic RNAs. Acts as a genome-linked replication primer.; Covalently linked to the 5'-end of both the positive-strand and negative-strand genomic RNAs. Acts as a genome-linked replication primer.; Covalently linked to the 5'-end of both the positive-strand and negative-strand genomic RNAs. Acts as a genome-linked replication primer.; Cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, binds to viral RNA and thus influences viral genome replication. RNA and substrate bind cooperatively to the protease.; RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals. Covalently attaches UMP to a tyrosine of VPg, which is used to prime RNA synthesis. The positive stranded RNA genome is first replicated at virus induced membranous vesicles, creating a dsRNA genomic replication form. This dsRNA is then used as template to synthesize positive stranded RNA genomes. ss(+)RNA genomes are either translated, replicated or encapsidated.
  • 亞細胞定位:
    [Capsid protein VP3]: Virion. Host cytoplasm.; [Capsid protein VP1]: Virion. Host cytoplasm.; [Capsid protein VP2]: Virion. Host cytoplasm.; [Protein 2B]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.; [Protein 2C]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.; [Protein 3A]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.; [Protein 3B-1]: Virion.; [Protein 3B-2]: Virion.; [Protein 3B-3]: Virion.; [Protease 3C]: Host cytoplasm.; [RNA-directed RNA polymerase 3D-POL]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Picornaviruses polyprotein family


主站蜘蛛池模板: 国产精品久久国产精麻豆99网站| 西西人体做爰大胆gogo| 国产 一二三四五六| 黑人大战亚洲人精品一区| 在线不卡日本v二区到六区| 久久精品囯产精品亚洲| 国产剧情无码播放在线看| 久久精品成人亚洲另类欧美| 国产美女裸体无遮挡免费视频 | 久久久无码一区二区三区| 久久精品中文无码资源站| 天天躁夜夜躁狠狠躁2021| 无人去码一码二码三码区| 2021亚洲国产成a在线| 亚洲精品久久夜色撩人男男小说| 亚洲国产一区二区三区在线观看| 亚洲国产精品久久精品| 99蜜桃臀久久久欧美精品网站| 久久综合伊人九色综合| 国产午夜鲁丝片av无码免费| 国产精品成人精品久久久| 99国产精品白浆在线观看免费 | 日日大香人伊一本线久| 亚洲人色婷婷成人网站在线观看| 波多野结衣乳巨码无在线观看| 国产精品情侣呻吟对白视频| 久久五月丁香激情综合| 国产欧美综合在线观看第十页| 麻豆成人久久精品综合网址| 小宝极品内射国产在线| 大伊香蕉精品视频在线天堂| 无码人妻精品丰满熟妇区| 一本加勒比hezyo中文无码| 亚洲毛片αv无线播放一区 | 美女张开腿让男人桶爽| 亚洲a∨国产av综合av网站| 精品国产成人高清在线观看| 人妻丰满被色诱中文字幕| 中文字幕人妻伦伦| 内射视频←www夜| 国内老熟妇乱子伦视频|