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  4. Recombinant Feline calicivirus Genome polyprotein (ORF1), partial

Recombinant Feline calicivirus Genome polyprotein (ORF1), partial

  • 中文名稱：
    Recombinant Feline calicivirus Genome polyprotein(ORF1) ,partial
  • 貨號(hào)：
    CSB-YP724042FAAR
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Feline calicivirus Genome polyprotein(ORF1) ,partial
  • 貨號(hào)：
    CSB-EP724042FAAR
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Feline calicivirus Genome polyprotein(ORF1) ,partial
  • 貨號(hào)：
    CSB-EP724042FAAR-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Feline calicivirus Genome polyprotein(ORF1) ,partial
  • 貨號(hào)：
    CSB-BP724042FAAR
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Feline calicivirus Genome polyprotein(ORF1) ,partial
  • 貨號(hào)：
    CSB-MP724042FAAR
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ORF1
  • Uniprot No.：
  • 別名：
    ORF1; Genome polyprotein [Cleaved into: Protein p5.6; Protein p32; NTPase; EC 3.6.1.15; p39); Protein p30; Viral genome-linked protein; VPg; p13); Protease-polymerase p76; Pro-Pol; EC 2.7.7.48; EC 3.4.22.66)]
  • 種屬：
    Feline calicivirus (strain Cat/United States/Urbana/1960) (FCV)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    NTPase presumably plays a role in replication. Despite having similarities with helicases, does not seem to display any helicase activity.; Viral genome-linked protein is covalently linked to the 5'-end of the positive-strand, negative-strand genomic RNAs and subgenomic RNA. Acts as a genome-linked replication primer. May recruit ribosome to viral RNA thereby promoting viral proteins translation.; Protease-polymerase p76 processes the polyprotein: Pro-Pol is first released by autocleavage, then all other proteins are cleaved. Cleaves host translation initiation factor eIF4G1, eIF4G2 and PABP1 thereby inducing a shutdown of host protein synthesis. This shutdown may not prevent viral mRNA from being translated since viral Vpg replaces the cap. May cleave host polyadenylate-binding protein thereby inhibiting cellular translation. It is also an RNA-directed RNA polymerase which replicates genomic and antigenomic viral RNA by recognizing specific signals. Transcribes also a subgenomic mRNA by initiating RNA synthesis internally on antigenomic RNA. This sgRNA codes for structural proteins. Catalyzes the covalent attachment VPg with viral RNAs.
  • 基因功能參考文獻(xiàn)：
    1. Remarkably, while the core of feline calicivirus VPg contains a well-defined three-helix bundle, the murine norovirus VPg core has just the first two of these secondary structure elements. PMID: 23487472
    2. results demonstrate that nucleolin is a nucleolar component that interacts with viral RNA and NS6/7 and is required for feline calicivirus replication PMID: 21680514
    3. Together, the data demonstrate that the p32, p39 and p30 proteins of FCV locate to the ER and lead to reorganization of ER membranes. PMID: 19906938
  • 數(shù)據(jù)庫鏈接：

    KEGG: vg:1502252



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