在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Escherichia coli Signal recognition particle protein (ffh)

Recombinant Escherichia coli Signal recognition particle protein (ffh)

  • 中文名稱：
    大腸桿菌ffh重組蛋白
  • 貨號：
    CSB-YP314184ENV
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大腸桿菌ffh重組蛋白
  • 貨號：
    CSB-EP314184ENV
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大腸桿菌ffh重組蛋白
  • 貨號：
    CSB-EP314184ENV-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大腸桿菌ffh重組蛋白
  • 貨號：
    CSB-BP314184ENV
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大腸桿菌ffh重組蛋白
  • 貨號：
    CSB-MP314184ENV
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ffh
  • Uniprot No.：
  • 別名：
    ffh; b2610; JW5414; Signal recognition particle protein; Fifty-four homolog; Ffh; p48
  • 種屬：
    Escherichia coli (strain K12)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-453
  • 氨基酸序列
    MFDNLTDRLS RTLRNISGRG RLTEDNVKDT LREVRMALLE ADVALPVVRE FINRVKEKAV GHEVNKSLTP GQEFVKIVRN ELVAAMGEEN QTLNLAAQPP AVVLMAGLQG AGKTTSVGKL GKFLREKHKK KVLVVSADVY RPAAIKQLET LAEQVGVDFF PSDVGQKPVD IVNAALKEAK LKFYDVLLVD TAGRLHVDEA MMDEIKQVHA SINPVETLFV VDAMTGQDAA NTAKAFNEAL PLTGVVLTKV DGDARGGAAL SIRHITGKPI KFLGVGEKTE ALEPFHPDRI ASRILGMGDV LSLIEDIESK VDRAQAEKLA SKLKKGDGFD LNDFLEQLRQ MKNMGGMASL MGKLPGMGQI PDNVKSQMDD KVLVRMEAII NSMTMKERAK PEIIKGSRKR RIAAGCGMQV QDVNRLLKQF DDMQRMMKKM KKGGMAKMMR SMKGMMPPGF PGR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
  • 基因功能參考文獻：
    1. Here, theauthors show that the C-terminal helix of the signal-sequence-binding domain of signal recognition particle penetrates into the ribosomal tunnel and contacts the intra-tunnel loop of ribosomal protein uL23. PMID: 28134917
    2. The kinetic analysis indicate that, at cellular concentrations of ribosomes and signal recognition particle (SRP), signal-anchor sequence (SAS) rapidly binds to translating ribosomes prior to the emergence of an SAS and forms an initial complex that rapidly rearranges to a more stable engaged complex. PMID: 29149347
    3. Data indicate that the sigma factor 32 (sigma32)-Ffh (the protein subunit of signal recognition particle (SRP) interaction was significantly affected by mutations in this region that compromise the feedback regulation. PMID: 27052372
    4. The cryo-electron microscopy structure of this 'false' early complex with EspP revealed an ordered M domain of SRP protein Ffh making two ribosomal contacts, and the NG domains of Ffh and FtsY forming a distorted, flexible heterodimer. PMID: 23563142
    5. Data indicate that Escherichia coli Ffh protein bound to the large subunit of mitochondrial ribosomes, and could relieve, to some degree, the defect of Saccharomyces cerevisiae Oxa1 mutants. PMID: 23198851
    6. Overexpression the M domain of Ffh inhibits the expression of membrane proteins. PMID: 20714446
    7. crystal structure of the SRP:SR complex at 3.9 angstrom resolution and biochemical data revealing that the activated SRP:SR GTPase complex binds the distal end of the SRP hairpin RNA where GTP hydrolysis is stimulated PMID: 21330537
    8. Results suggest that indeed, while FtsY-depletion affects earlier steps in the pathway (possibly translation), Ffh-depletion disrupts membrane protein biogenesis later during the targeting pathway by preventing their functional assembly in the membrane. PMID: 20161748
    9. MsrA and MsrB are required to repair Ffh oxidized by reactive oxygen species produced by aerobic metabolism, establishing an as-yet undescribed link between protein targeting and oxidation PMID: 15057280
    10. Ffh and FtsY form a complex in which both proteins reciprocally activate the GTPase reaction of one another PMID: 15383838
    11. In free Ffh, the binding sites for 4.5S RNA and FtsY are occluded by strong domain-domain interactions. PMID: 15923378
    12. FRET analysis of conformation of signal recognition particle protein Ffh from Escherichia coli PMID: 16005894
    13. The signal recognition particle (SRP) RNA may coordinate the interaction of the SRP and the SRP receptor with ribosome recruitment and transfer to the translocon, explaining why the SRP RNA is an indispensable component of the protein targeting machinery. PMID: 17507650
    14. the SRP and SR GTPases, without recruiting external regulatory factors, constitute a self-sufficient system that provides exquisite spatial and temporal control of a complex cellular process PMID: 19174514

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
  • 蛋白家族：
    GTP-binding SRP family, SRP54 subfamily
  • 數據庫鏈接：


主站蜘蛛池模板： 18禁黄网站禁片免费观看女女| 婷婷丁香社区| 亚洲成a人片在线观看高清| 免费无码av片在线观看潮喷| 午夜嘿嘿嘿在线观看| 久久精品国产99久久久| 香港三级精品三级在线专区| 久久午夜无码鲁丝片秋霞| 国产杨幂丝袜av在线播放| 中文国产成人精品久久app| 老鲁夜夜老鲁| 日本熟日本熟妇在线视频| 亚洲精品卡一卡三卡四卡乱码| 让少妇爽到高潮视频| 午夜影视免费| 国产乱妇乱子在线播放视频| 无码东京热一区二区三区| 日产精品卡2卡三卡乱码网站| 野外性史欧美k8播放| 国产69精品久久久久人妻| 色综合久久久久综合体桃花网| 欧美精品中文字幕亚洲专区| 亚洲国产成人精品无码一区二区 | 成人无码影片精品久久久| 好吊妞无缓冲视频观看| 92午夜少妇极品福利无码电影| 人妻三级日本三级日本三级极| 亚洲日韩一区二区| 乱人伦中文字幕成人网站在线| 国产999精品久久久久久| 国产区精品系列在线观看| 2019亚洲午夜无码天堂| 无码人妻丰满熟妇a片护士| 暖暖视频日本在线观看| 尤物av无码国产在线看| 人妻无码熟妇乱又伦精品视频| 成在线人视频免费视频| 国产亚洲欧美日韩夜色凹凸成人 | 日本55丰满熟妇厨房伦| 99国产欧美另类久久久精品| 99久久精品费精品国产|