在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Escherichia coli Sensor protein CpxA (cpxA), partial

Recombinant Escherichia coli Sensor protein CpxA (cpxA), partial

  • 中文名稱：
    Recombinant Escherichia coli Sensor protein CpxA(cpxA),partial
  • 貨號：
    CSB-YP360072ENV
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Escherichia coli Sensor protein CpxA(cpxA),partial
  • 貨號：
    CSB-EP360072ENV
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Escherichia coli Sensor protein CpxA(cpxA),partial
  • 貨號：
    CSB-EP360072ENV-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Escherichia coli Sensor protein CpxA(cpxA),partial
  • 貨號：
    CSB-BP360072ENV
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Escherichia coli Sensor protein CpxA(cpxA),partial
  • 貨號：
    CSB-MP360072ENV
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    cpxA
  • Uniprot No.：
  • 別名：
    cpxA; ecfB; eup; ssd; b3911; JW3882Sensor histidine kinase CpxA; EC 2.7.13.3
  • 種屬：
    Escherichia coli (strain K12)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Histidine kinase member of the two-component regulatory system CpxA/CpxR which responds to envelope stress response by activating expression of downstream genes including cpxP, degP, dsbA and ppiA. Activates CpxR by phosphorylation; has autokinase, phosphotransferase and (in the presence of Mg(2+) and/or ATP or ADP) phosphatase activity. The kinase activity is inhibited by periplasmic accessory protein CpxP; proteolysis of CpxP relieves inhibition. Involved in several diverse cellular processes, including the functioning of acetohydroxyacid synthetase I, the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synthesis, translocation, or stability of cell envelope proteins. Activates transcription of periplasmic protease degP, probably by phosphorylating the cognate response protein CpxR; overexpression of an outer membrane lipoprotein NlpE also leads to transcription of degP via CpxRA. Required for efficient binding of stationary phase cells to hydrophobic surfaces, part of the process of biofilm formation.
  • 基因功能參考文獻：
    1. The cpxA mutant was attenuated for virulence in the kidney but not in the bladder or urine. PMID: 29311237
    2. X-ray structures of the CpxA reveals allosteric switching mechanism, according to which CpxR binding to one CpxA protomer triggers autophosphorylation in the second protomer. PMID: 28552574
    3. Experimental modifications R296A and R296D of CpxA have been observed to reduce also the CpxA activity. These observations agree with the destabilization of the R296/F403 stacking, and could be the sign of the transmission of a conformational event taking place in HAMP to the auto-phosphorylation site of histidine kinase. PMID: 27124288
    4. CpxP modulates the activity of the Cpx system by dynamic interaction with CpxA in response to specific stresses. PMID: 25207645
    5. Segmental helical motions and dynamical asymmetry modulate CpxA autophosphorylation. PMID: 24492262
    6. Different regions on the periplasmic domain of CpxA modulate signal transduction. PMID: 21349329
    7. Mutations in CpxA individually increase phosphorylation of OmpR and phosphatase activity against phospho-OmpR which results in a circuit that is responsive to changes in CpxA stimulus. PMID: 21179024
    8. plays a role in regulation of UNG (uracil-dna glycoylase) gene expression and in controlling mutation rate PMID: 15576781

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell inner membrane; Multi-pass membrane protein.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲欧美中文日韩在线v日本| 久久国产欧美成人av| 国产精品亚洲玖玖玖在线观看| 精品国产高清毛片a片看| 377p欧洲日本亚洲大胆| 色狠狠成人综合网| 婷婷无套内射影院| 久久天天躁狠狠躁夜夜av浪潮| 国产成人精品a∨一区二区| 黄页网站视频免费大全| 亚洲一区二区三区四区| 夜夜影院未满十八勿进| 小泽玛莉亚一区二区视频在线| 国产成人av免费网址| 日韩欧美精品有码在线| 国产精品免费看久久久无码| 在线精品国产成人综合| 国产精品自在在线午夜出白浆| 亚洲色无码专区在线播放| 亚洲欧美偷拍另类a∨| 国外亚洲成av人片在线观看| 人妻熟女一区二区aⅴ林晓雪| 国内精品视这里只有精品| 18禁无遮挡羞羞啪啪免费网站| 国产电影一区二区三区| 亚洲 欧美 国产 日韩 中文字幕 | 国产色无码精品视频免费| 熟妇女人妻丰满少妇中文字幕| 九九影院午夜理论片少妇| 亚洲国产制服丝袜高清在线| 国产又爽又粗又猛的视频| 日本乱妇乱子视频网站-百度| 久草热8精品视频在线观看| 真实国产乱子伦对白在线播放| 在线成人一区二区| 欧美孕妇变态重口另类| 成人h动漫无码网站久久| 亚洲五月综合缴情在线观看| 黑人玩弄人妻中文在线| 狠狠躁夜夜躁人人爽天天不卡| 亚洲va天堂va欧美片a在线|