在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Escherichia coli Ribonucleoside-diphosphate reductase 1 subunit alpha (nrdA)

  • 中文名稱:
    大腸桿菌nrdA重組蛋白
  • 品名簡稱:
    Recombinant E.coli nrdA protein
  • 貨號:
    CSB-EP355522ENV
  • 說明書:
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    nrdA
  • Uniprot No.:
  • 別名:
    nrdA; dnaF; b2234; JW2228; Ribonucleoside-diphosphate reductase 1 subunit alpha; EC 1.17.4.1; Protein B1; Ribonucleoside-diphosphate reductase 1 R1 subunit; Ribonucleotide reductase 1
  • 種屬:
    Escherichia coli (strain K12)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    101.8kDa
  • 表達區域:
    1-761aa
  • 氨基酸序列
    MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-SUMO-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.
  • 基因功能參考文獻:
    1. Elimination of 6 helicases lowered NrdA production further, whereas overexpression of any RNA helicase partially reversed the downregulation. UV stress completely reversed down-regulation of NrdA production PMID: 26574793
    2. The present results identifying a large, new set of E. coli mutator strains with mutations of nrdAB ribonucleotide reductase(RNR)confirm the important control that RNR exerts on the cellular mutation rate and provide novel insights into the RNR feedback regulatory mechanisms. PMID: 22417940
    3. RNR101 is unstable at 42 degrees C ; its degradation is prevented by rifampicin; inactivation of DnaA protein by allows chromosome replication in absence of rifampicin and suppresses nucleoid segregation and cell division defects seen in nrdA101 mutant at 42 degrees C PMID: 21527473
    4. The report three independent methods that establish that Y(356) is the predominant location (85-90%) of the radical, with the remaining 10-15% delocalized onto Y(731) and Y(730) in alpha2. PMID: 21967342
    5. The authors propose that RecA is required to maintain the integrity of the reversed forks in the nrdA101 mutant under certain restrictive conditions, supporting the relationship between DNA replication and recombination enzymes. PMID: 21441507
    6. The authors show that the binding of DnaA on the NrdAB promoter can either activate or repress transcription as a function of its concentration and its nucleotide-bound state. PMID: 20487274
    7. analysis of key residues in the dimerization process of ribonucleotide reductase protein R1 PMID: 15699052
    8. There is an indirect relationship between NDP reductase and the chromosome segregation machinery through the maintenance of the proposed replication hyperstructure. PMID: 17124544
    9. it is proposed that an altered NDP reductase, as a component of the replication machinery, impairs the progression of the replication fork, contributing to the lengthening of the C period in the nrdA101 mutant at the permissive temperature PMID: 17322311

    顯示更多

    收起更多

  • 蛋白家族:
    Ribonucleoside diphosphate reductase large chain family
  • 數據庫鏈接:


主站蜘蛛池模板: 丰满人妻被黑人连续中出| 亚洲国产精品一区二区动图| 免费人成网站视频在线观看国内| 精品国产午夜理论片不卡精品| 亚洲码欧美码一区二区三区| 国产无套乱子伦精彩是白视频| 色欲久久人妻内射| 欧美日产欧美日产国产精品| 国产熟妇乱xxxxx大屁股网| 国产成a人片在线观看视频下载| 久久精品无码免费不卡 | 97国产一区二区三区四区久久| 国产人成无码视频在线观看| 国产麻豆剧传媒精品av | 国内精品乱码卡一卡2卡三卡新区| 欧美日韩中文在线字幕视频| 亚洲精品国产suv| 免费国产黄网站在线观看视频| 无码国产玉足脚交极品网站| 狠狠色噜噜狠狠狠狠777米奇小说| 成人性生交大片免费看视频app| 综合图区亚洲另类偷窥| 久久ee热这里只有精品| 亚洲无人区一区二区三区| 国模无码一区二区三区| 一区二区久久久久草草| 亚洲aⅴ天堂av天堂无码 | 亚洲精品久久婷婷丁香51| 狠狠色综合7777久夜色撩人ⅰ| 日本又色又爽又黄的视频免 | 亚洲美女又黄又爽在线观看| 乱码丰满人妻一二三区| 又大又粗又爽又黄的少妇毛片| 久久麻豆成人精品av| 麻豆av一区二区天美传媒| 潮喷大喷水系列无码视频| 女上男下啪啪激烈高潮无遮盖| 久久国产精品无码一区二区三区| 日韩精品无码一区二区| 爆乳高潮喷水无码正在播放| 亚洲精品www久久久|