在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Escherichia coli Chaperone protein YajL (yajL)

Recombinant Escherichia coli Chaperone protein YajL (yajL)

  • 中文名稱：
    大腸桿菌yajL重組蛋白
  • 貨號：
    CSB-YP676104ENV
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    大腸桿菌yajL重組蛋白
  • 貨號：
    CSB-EP676104ENV
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    大腸桿菌yajL重組蛋白
  • 貨號：
    CSB-EP676104ENV-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    大腸桿菌yajL重組蛋白
  • 貨號：
    CSB-BP676104ENV
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    大腸桿菌yajL重組蛋白
  • 貨號：
    CSB-MP676104ENV
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    yajL
  • Uniprot No.：
  • 別名：
    yajL; thiJ; b0424; JW5057; Protein/nucleic acid deglycase 3; EC 3.1.2.-; EC 3.5.1.-; EC 3.5.1.124; Chaperone protein YajL; Maillard deglycase
  • 種屬：
    Escherichia coli (strain K12)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-196
  • 氨基酸序列
    MSASALVCLA PGSEETEAVT TIDLLVRGGI KVTTASVASD GNLAITCSRG VKLLADAPLV EVADGEYDVI VLPGGIKGAE CFRDSTLLVE TVKQFHRSGR IVAAICAAPA TVLVPHDIFP IGNMTGFPTL KDKIPAEQWL DKRVVWDARV KLLTSQGPGT AIDFGLKIID LLVGREKAHE VASQLVMAAG IYNYYE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Is able to repair glycated serum albumin, collagen, glyceraldehyde-3-phosphate dehydrogenase, and fructose biphosphate aldolase. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE) that cause irreversible damage. Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA. Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair. However, is less efficient than Hsp31 and YhbO, suggesting that YajL might be preferentially dedicated to protein repair. Displays a covalent chaperone activity with sulfenylated thiol proteins by forming mixed disulfides with members of the thiol proteome, and preferentially with sulfenylated cellular proteins, upon oxidative stress; these mixed disulfides can be subsequently reduced by low-molecular-weight thiols to regenerate YajL and reduced proteins. Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Confers resistance to oxidative stress. Plays an important role in protection against electrophile/carbonyl stress. The chaperone activity reported for YajL is probably recruited to execute its deglycase activity, to interact with non-native glycated proteins and gain access to partially buried glycated sites. Also displays an apparent glyoxalase activity that in fact reflects its deglycase activity.
  • 基因功能參考文獻：
    1. The Parkinsonism-associated protein DJ-1 and its bacterial homologs deglycase 1/Hsp31, deglycase 2/YhbO, and deglycase 3/YajL function as deglycases that repair proteins and nucleotides from endogeneous glycation by glyoxal and methylglyoxal. DJ-1, deglycase 1 and deglycase 2 repair glyoxal- and methylglyoxal-glycated substrates, whereas deglycase 3 principally repairs glyoxal-glycated substrates. PMID: 29932913
    2. Purified YajL, YhbO and ElbB exhibited glyoxalase activity with different substrate specificities, optimal pHs and metal effects. PMID: 26678554
    3. Moreover, yhbO and yajL mutants display decreased viability in methylglyoxal- or glucose-containing media PMID: 26774339
    4. protein defects resulting from the yajL mutation trigger the onset of a robust and global stress response in a prokaryotic model of DJ-1-associated Parkinsonism. PMID: 23292772
    5. YajL and possibly DJ-1 function as covalent chaperones involved in the detection of sulfenylated proteins by forming mixed disulfides with them and that these disulfides are subsequently reduced by low-molecular-weight thiols. PMID: 22321799

    顯示更多

    收起更多

  • 蛋白家族：
    Peptidase C56 family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 免费无码黄十八禁网站在线观看 | 国产果冻豆传媒麻婆精东| 午夜大片男女免费观看爽爽爽尤物| 国语自产精品视频在线看| 福利一区二区三区视频在线观看| 国产女同疯狂作爱系列| 国产精品激情欧美可乐视频| 又爽又黄无遮挡高潮视频网站| 吃奶呻吟张开双腿做受在线播放 | 日本真人边吃奶边做爽电影| 人人妻人人澡人人爽欧美一区双| 日本japanese丰满白浆| 免费无码又爽又刺激一高潮| 麻花豆传媒剧国产免费mv观看| 午夜成人鲁丝片午夜精品 | 亚欧无线一线二线三线区别| 免费高清av一区二区三区| 日本欧美亚洲中文在线观看| 波多野结衣潮喷视频无码42| 国产av熟女一区二区三区| 国产影片中文字幕| 人妻熟女av一区二区三区| 国产精品系列无码专区| 女人高潮内射99精品| 精品人妻无码一区二区三区抖音 | 日韩精品无码一区二区三区| 国产成人精品午夜福利在线观看 | 亚洲人成人无码网www国产| 四虎亚洲精品无码| 忘忧草影院在线www韩国日本| 天堂网在线观看| 国产免费久久精品99久久| 羞羞视频在线观看| 日韩人妻无码精品专区906188| 亚洲第一无码av无码专区| 天天综合网天天综合色| av人摸人人人澡人人超碰小说 | 波多野结av在线无码中文| 麻豆果冻传媒2021精品传媒一区| 欧美疯狂性受xxxxx另类| 亚洲成年网站青青草原 |