在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Epstein-Barr virus Secreted protein BARF1 (BARF1)

In Stock
  • 貨號:
    CSB-EP317825EFC
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    BARF1
  • Uniprot No.:
  • 別名:
    33 kDa early protein p33
  • 種屬:
    Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    28.4 kDa
  • 表達區域:
    21-221aa
  • 氨基酸序列
    VTAFLGERVTLTSYWRRVSLGPEIEVSWFKLGPGEEQVLIGRMHHDVIFIEWPFRGFFDIHRSANTFFLVVTAANISHDGNYLCRMKLGETEVTKQEHLSVVKPLTLSVHSERSQFPDFSVLTVTCTVNAFPHPHVQWLMPEGVEPAPTAANGGVMKEKDGSLSVAVDLSLPKPWHLPVTCVGKNDKEEAHGVYVSGYLSQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro.
  • 基因功能參考文獻:
    1. Epstein Barr virus-encoded BARF1 promotes cell proliferation in stomach cancer by upregulating NFkappaB and miR-146a and downregulating SMAD4, thereby contributing to EBV-induced stomach cancer progression. PMID: 27438138
    2. siRNA-mediated BARF1 down-regulation induces caspase-dependent apoptosis via the mitochondrial pathway through modulation of Bcl-2/BAX ratio in AG876 and Hone-Akata cells. PMID: 25740140
    3. In BARF1-transfected cells, cell growth was activated and its protein was found both in culture medium and cellular compartment (membrane, cytoplasm and nuclei). PMID: 23458996
    4. These results indicate that BARF1 blockade of CSF-1 signaling is an important immune evasion strategy for efficient acute EBV infection and a significant determinant for virus setpoint during persistent EBV infection. PMID: 23300447
    5. M-CSF was shown to interact with Epstein-Barr virus-encoded BARF1 via the protruding N-terminal loops involving Val38 and Ala84. PMID: 23061794
    6. Studies indicate that BARF1 is expressed as a latent gene in nasopharyngeal carcinoma (NPC), and that BARF1 contributes to the tumorigenicity of NPC cells. PMID: 22210180
    7. The N- and O-glycans were partially characterized and it was demonstrated that both modifications are required for active secretion of the BARF1 protein via the classical pathway. PMID: 17872516

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 數據庫鏈接:

    KEGG: vg:3783772



主站蜘蛛池模板: 少妇午夜啪爽嗷嗷叫视频| 水蜜桃亚洲一二三四在线| 性做久久久久久免费观看 | 青青草97国产精品免费观看| 国产av麻豆mag剧集| 久久伊99综合婷婷久久伊| 色欲香天天综合网站| 丰满人妻翻云覆雨呻吟视频| 艳妇臀荡乳欲伦69调教视频| 欧美亚洲日本国产综合在线| 九九99精品久久久久久综合| 欧美黑人大战白嫩在线| 精品人妻少妇一区二区三区不卡| 成人无码a片一区二区三区免| 久久天天躁狠狠躁夜夜2o2o| 欧美日韩亚洲国内综合网| 成熟丰满熟妇高潮xxxxx视频 | 97成人精品区在线播放| 亚洲日韩欧美一区二区三区| 乌克兰少妇性做爰| 国产精品久久无码不卡| 久久欧美一区二区三区性牲奴| 粉色午夜视频| 男人的天堂av网站| 亚洲精品综合在线影院| 无码日韩精品一区二区三区免费| 亚洲а∨天堂久久精品2021| 国产精品亚洲w码日韩中文| 日99久9在线 | 免费| 国产在线精品二区| 五月天激情电影| 欧美日产亚洲国产精品| 亚洲午夜精品久久久久久人妖| 国产中文欧美日韩在线| 久久精品免视看国产成人| 在线观看成人无码中文av天堂不卡| 国产精品人成视频免费999 | 自拍偷自拍亚洲精品第1页| 亚洲精华国产精华精华液网站| 1000部又爽又黄无遮挡的视频 | 欧美国产亚洲日韩在线二区 |