在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Epstein-Barr virus Secreted protein BARF1 (BARF1)

In Stock
  • 貨號:
    CSB-EP317825EFC
  • 規格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    BARF1
  • Uniprot No.:
  • 別名:
    33 kDa early protein p33
  • 種屬:
    Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    28.4 kDa
  • 表達區域:
    21-221aa
  • 氨基酸序列
    VTAFLGERVTLTSYWRRVSLGPEIEVSWFKLGPGEEQVLIGRMHHDVIFIEWPFRGFFDIHRSANTFFLVVTAANISHDGNYLCRMKLGETEVTKQEHLSVVKPLTLSVHSERSQFPDFSVLTVTCTVNAFPHPHVQWLMPEGVEPAPTAANGGVMKEKDGSLSVAVDLSLPKPWHLPVTCVGKNDKEEAHGVYVSGYLSQ
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro.
  • 基因功能參考文獻:
    1. Epstein Barr virus-encoded BARF1 promotes cell proliferation in stomach cancer by upregulating NFkappaB and miR-146a and downregulating SMAD4, thereby contributing to EBV-induced stomach cancer progression. PMID: 27438138
    2. siRNA-mediated BARF1 down-regulation induces caspase-dependent apoptosis via the mitochondrial pathway through modulation of Bcl-2/BAX ratio in AG876 and Hone-Akata cells. PMID: 25740140
    3. In BARF1-transfected cells, cell growth was activated and its protein was found both in culture medium and cellular compartment (membrane, cytoplasm and nuclei). PMID: 23458996
    4. These results indicate that BARF1 blockade of CSF-1 signaling is an important immune evasion strategy for efficient acute EBV infection and a significant determinant for virus setpoint during persistent EBV infection. PMID: 23300447
    5. M-CSF was shown to interact with Epstein-Barr virus-encoded BARF1 via the protruding N-terminal loops involving Val38 and Ala84. PMID: 23061794
    6. Studies indicate that BARF1 is expressed as a latent gene in nasopharyngeal carcinoma (NPC), and that BARF1 contributes to the tumorigenicity of NPC cells. PMID: 22210180
    7. The N- and O-glycans were partially characterized and it was demonstrated that both modifications are required for active secretion of the BARF1 protein via the classical pathway. PMID: 17872516

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 數據庫鏈接:

    KEGG: vg:3783772



主站蜘蛛池模板: 狠狠色丁香婷婷综合尤物| 国产女人乱人伦精品一区二区| 影视先锋男人无码在线| 国产东北肥熟老胖女| 国产va在线观看免费| 国产超碰人人爱被ios解锁| 亚洲精品久久7777777国产| 人妻插b视频一区二区三区| 蜜桃臀无码内射一区二区三区| 强开小婷嫩苞又嫩又紧视频韩国| 欧美老妇bbbwwbbbww| 日本亚欧热亚洲乱色视频| 国产三级做爰在线播放| 人妻激情偷乱视频一区二区三区| 美女裸体十八禁免费网站| 五月激激激综合网亚洲| 男人扒开女人双腿猛进免费视频| 亚洲欧洲日产国无高清码图片 | 大又大粗又爽又黄少妇毛片| 亚洲精品国产精品乱码视色| 国产精品亚洲综合久久系列| 亚洲伊人久久精品酒店| 久久香蕉国产线看观看精品yw| 久久人妻无码中文字幕| 成人午夜福利院在线观看| 成人18禁深夜福利网站app免费 | 亚洲1卡二卡三新区2022| 日韩人妻无码精品久久久不卡| 久久99精品国产99久久6尤物 | 国产又色又刺激高潮视频| 亚洲欧美日韩精品久久| 亚洲最大无码中文字幕| 挺进邻居丰满少妇的身体| 俄罗斯老熟妇色xxxx| 无码人妻精品一区二区三区在线| 欧美色就是色| 国产av福利久久| 国产内射老熟女aaaa| 成人国产欧美大片一区| 国产按头口爆吞精在线视频| 蜜臀av性久久久久蜜臀aⅴ|