在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Ephrin receptor 1 (vab-1), partial

Recombinant Ephrin receptor 1 (vab-1), partial

  • 中文名稱：
    秀麗隱桿線蟲vab-1重組蛋白
  • 貨號(hào)：
    CSB-YP526454CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲vab-1重組蛋白
  • 貨號(hào)：
    CSB-EP526454CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲vab-1重組蛋白
  • 貨號(hào)：
    CSB-EP526454CXY-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲vab-1重組蛋白
  • 貨號(hào)：
    CSB-BP526454CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲vab-1重組蛋白
  • 貨號(hào)：
    CSB-MP526454CXY
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    vab-1
  • Uniprot No.：
  • 別名：
    vab-1; M03A1.1; Ephrin receptor 1; EC 2.7.10.1; Tyrosine-protein kinase Eph receptor; Variable abnormal protein 1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor for members of the ephrin family. Receptor for major sperm proteins (MSPs), that functions as sperm-sensing checkpoint which inhibits oocyte meiotic maturation and ovulation when sperm are not available for fertilization. Specifically, functions to negatively regulates oocyte maturation and MAPK activation in the absence of MSPs. Required for the MSP-mediated increase in the basal sheath cell contraction rate in somatic cells. Phosphorylates phosphatase daf-18/PTEN which probably promotes daf-18 degradation. By inactivating daf-18, regulates positively insulin-like daf-2 signaling cascade. Involved in interactions between neuronal substrate cells and a migrating epithelial sheet in head epidermis morphogenesis. Also required for cell movements following gastrulation and during ventral closure of the epidermis. Might play a role in spermatheca morphogenesis. Involved in axon guidance of SDQL neurons during neurogenesis.
  • 基因功能參考文獻(xiàn)：
    1. Overall locomotion speed increased with increasing nicotine concentration in all tested mutant strains except in the vab-1 mutants PMID: 26574927
    2. Analysis of EFN-1(VAB2) expression and tissue-specific requirements is consistent with a model in which VAB-1 acts in amphid neurons, interacting with EFN-1 expressed on surrounding cells. PMID: 23979582
    3. VAB-1/Eph RTK can stop axonal outgrowth by inhibiting filopodia formation at the growth cone by activating Arp2/3 through a VAB-1/NCK-1/WSP-1 complex and by inhibiting UNC-34/Ena activity PMID: 22383893
    4. The germline apoptosis function of VAB-1 impacts specific cell death pathways, and may act in parallel to extracellular signal-regulated kinase MAPK signaling. PMID: 22240896
    5. Bridge formation requires VAB-1 kinase-dependent extension of presumptive bridge cells over scaffold cells toward the ventral midline during body wall closure PMID: 22197242
    6. identified the VAB-1 Eph receptor protein-tyrosine kinase as a major sperm protein receptor PMID: 12533508
    7. Data show that SAX-3/Robo functions with the VAB-1 Eph receptor for gastrulation cleft closure and ventral epidermal enclosure. PMID: 16033794
    8. VAB-1 switches from a negative regulator into a redundant positive regulator of oocyte maturation upon binding to MSP. NMR-1 mediates this switch by controlling UNC-43 CaMKII activation at the oocyte cortex. PMID: 16267094
    9. VAB-1 Eph RTK is required for targeting or limiting axons and neuronal cells to specific regions, perhaps by transducing a repellent or stop cue. PMID: 16386725
    10. This study shows that mutations in ina-1 (alpha-integrin), as well as vab-1 (Eph receptor), and vab-2 (ephrin), display defects in embryonic muscle cell migration. PMID: 18452914
    11. Regulated endocytic trafficking of the VAB-1 MSP/Eph receptor contributes to the control of oocyte meiotic maturation. PMID: 18472420
    12. Hypoxia exerted its [adverse] effect on axon pathfinding at least in part through HIF-1-dependent regulation of the Eph receptor VAB-1. PMID: 18587389

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family, Ephrin receptor subfamily
  • 組織特異性：
    During ventral enclosure of the epidermis, expression is seen in clusters of presumptive head neuronal cells and several cells in the tail region. Early larvae show expression in the nerve ring and ventral nerve cord. Strong expression is also seen in the
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: cel:CELE_M03A1.1

    STRING: 6239.M03A1.1b

    UniGene: Cel.5002



主站蜘蛛池模板： 日本高清www无色夜在线视频| 亚洲熟女乱色综合亚洲图片| 亚洲精品成人无限看| 国产一区二区三区 韩国女主播| 日韩精品亚洲aⅴ在线影院| 日日摸日日碰夜夜爽亚洲| 特黄特色大片免费播放| 丰满饥渴老女人hd| 亚洲日韩欧美一区久久久久我| 97热久久免费频精品99| 超薄丝袜足j好爽在线| 婷婷丁香五月中文字幕| 国产精品久久777777| 欧美品无码一区二区三区在线蜜桃 | 夜夜躁狠狠躁日日躁202| 国内午夜熟妇又乱又伦| 欧美精品国产综合久久| 强奷人妻日本中文字幕| 亚洲性夜夜天天天| 亚洲中文字幕无码中文| 国产成年女人毛片80s网站| 国内精品久久久久久久97牛牛| 久久人人爽人人爽人人片av高请| 亚洲精品久久久久久成人 | 又大又粗又长的高潮视频| 精品综合久久久久久98| 五级黄高潮片90分钟视频| 成人午夜高潮免费视频在线观看| 亚洲 欧美 国产 综合免费| 亚洲中文字幕一区精品自拍| 无码人中文字幕| 天天综合色天天综合色h| 亚洲欧洲日本精品专线| 国产乱人无码伦av在线a | 亚洲有无码av在线播放| 欧美成人aaaa免费全部观看| www婷婷av久久久影片| 色 亚洲 日韩 国产 综合| 狼人亚洲国内精品自在线| 国产啪视频1000部免费| 色婷婷美国农夫综合激情亚洲|