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Recombinant Enterococcus faecium Vancomycin/teicoplanin A-type resistance protein VanA (vanA)

  • 中文名稱:
    Recombinant Enterococcus faecium Vancomycin/teicoplanin A-type resistance protein VanA(vanA)
  • 貨號:
    CSB-YP333043ELX
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Enterococcus faecium Vancomycin/teicoplanin A-type resistance protein VanA(vanA)
  • 貨號:
    CSB-EP333043ELX
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Enterococcus faecium Vancomycin/teicoplanin A-type resistance protein VanA(vanA)
  • 貨號:
    CSB-EP333043ELX-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Enterococcus faecium Vancomycin/teicoplanin A-type resistance protein VanA(vanA)
  • 貨號:
    CSB-BP333043ELX
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Enterococcus faecium Vancomycin/teicoplanin A-type resistance protein VanA(vanA)
  • 貨號:
    CSB-MP333043ELX
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    vanA
  • Uniprot No.:
  • 別名:
    vanA; Vancomycin/teicoplanin A-type resistance protein VanA; EC 6.1.2.1; D-alanine--D-lactate ligase; VanA ligase
  • 種屬:
    Enterococcus faecium (Streptococcus faecium)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-343
  • 氨基酸序列
    MNRIKVAILF GGCSEEHDVS VKSAIEIAAN INKEKYEPLY IGITKSGVWK MCEKPCAEWE NDNCYSAVLS PDKKMHGLLV KKNHEYEINH VDVAFSALHG KSGEDGSIQG LFELSGIPFV GCDIQSSAIC MDKSLTYIVA KNAGIATPAF WVINKDDRPV AATFTYPVFV KPARSGSSFG VKKVNSADEL DYAIESARQY DSKILIEQAV SGCEVGCAVL GNSAALVVGE VDQIRLQYGI FRIHQEVEPE KGSENAVITV PADLSAEERG RIQETAKKIY KALGCRGLAR VDMFLQDNGR IVLNEVNTLP GFTSYSRYPR MMAAAGIALP ELIDRLIVLA LKG
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Required for high-level resistance to glycopeptide antibiotics. D-Ala--D-Ala ligase of altered specificity which catalyzes ester bond formation between D-Ala and various D-hydroxy acids; produces a peptidoglycan which does not terminate in D-alanine but in D-lactate, thus preventing vancomycin or teicoplanin binding.
  • 基因功能參考文獻:
    1. Vancomycin-resistant Enterococcus faecium and Enterococcus faecalis in the West Balkans carry plasmids expressing vanA and vanB genes. PMID: 27351410
    2. Enterococcus faecium strains carrying both vanB and vanA are identified in hospitalized glycopeptide-resistant patients. PMID: 24092659
  • 亞細(xì)胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    D-alanine--D-alanine ligase family
  • 數(shù)據(jù)庫鏈接:

    KEGG: ag:CAA40215



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