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  4. Recombinant Drosophila nebulosa Period circadian protein (per)

Recombinant Drosophila nebulosa Period circadian protein (per)

  • 中文名稱：
    Recombinant Drosophila nebulosa Period circadian protein(per)
  • 貨號：
    CSB-YP308596DGM
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila nebulosa Period circadian protein(per)
  • 貨號：
    CSB-EP308596DGM
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila nebulosa Period circadian protein(per)
  • 貨號：
    CSB-EP308596DGM-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila nebulosa Period circadian protein(per)
  • 貨號：
    CSB-BP308596DGM
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila nebulosa Period circadian protein(per)
  • 貨號：
    CSB-MP308596DGM
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    per
  • Uniprot No.：
  • 別名：
    per; Period circadian protein; Fragment
  • 種屬：
    Drosophila nebulosa (Fruit fly)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-385
  • 氨基酸序列
    SSTETPPSYN QLNYNENLLR FFNSKPVTAP VPVELDPPKV ESSYVSSARE DARSTLSPVQ GFEGSGGSGS SGNFTTGSNL HMSSVTNTSN AGTGTSGTGN SGDGGGGGAG DGPGSGAVPP VTLTESLLNK HNDEMEKFML KNDRESRGWS GEKNKKSAND TLKMVEYSGP GPGHGHGIKR GGSHSWEGEA NKPKQQLTLN AGGMPPLVDI HASSSSLSKC QTSVAGGGGG GGAGSASGTC GTGNNGAGGG GGSNAQSSTN QYTQSGLSCT QNINLWPPFS VGITTPTSVL STHMAVAQSS FSPQHSLFPT FYYIPASIAA SSPASGTSPN PRPHKHTHVH PSSEQPSTSQ GAAATMPLQY MTGVMYPHPS LFYTHPAAAA ATAMV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Essential for biological clock functions. Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms. Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system. The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex. Light induces the degradation of TIM, which promotes elimination of PER. Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop. Behaves as a negative element in circadian transcriptional loop. Does not appear to bind DNA, suggesting indirect transcriptional inhibition.
  • 亞細胞定位：
    Nucleus. Cytoplasm, perinuclear region.


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