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  4. Recombinant Drosophila melanogaster cAMP-specific 3',5'-cyclic phosphodiesterase, isoform I (dnc), partial

Recombinant Drosophila melanogaster cAMP-specific 3',5'-cyclic phosphodiesterase, isoform I (dnc), partial

  • 中文名稱：
    黑腹果蠅dnc重組蛋白
  • 貨號：
    CSB-YP893842DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅dnc重組蛋白
  • 貨號：
    CSB-EP893842DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅dnc重組蛋白
  • 貨號：
    CSB-EP893842DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅dnc重組蛋白
  • 貨號：
    CSB-BP893842DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅dnc重組蛋白
  • 貨號：
    CSB-MP893842DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    dnc
  • Uniprot No.：
  • 別名：
    dnc; CG32498; cAMP-specific 3',5'-cyclic phosphodiesterase; isoform I; EC 3.1.4.53; Learning/memory process protein; Protein dunce
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Vital for female fertility. Required for learning/memory.
  • 基因功能參考文獻：
    1. Hangover acts as a nuclear RNA binding protein and we identified the phosphodiesterase 4d ortholog dunce as a target RNA. PMID: 28076795
    2. dunce knockdown in the mushroom body neurons impairs memory without significantly affecting acquisition. PMID: 25644700
    3. Dunce phosphodiesterase plays a major role in the spatial regulation of cAMP dynamics. PMID: 20188656
    4. These results indicate that calcium influx through acetylcholine receptors is increased in dunce and that calcium extrusion to the outside and/or calcium buffering are enhanced in dunce. PMID: 14660074
    5. Choice behavior in Drosophila involves central nervous learning and memory operating via cyclic AMP signaling pathways PMID: 17180701
    6. flies responding to visual novelty revealed attention-like processes with stereotypical temporal properties; these processes were modulated by genes involved in short-term memory formation, namely dunce and rutabaga PMID: 17363675

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  • 蛋白家族：
    Cyclic nucleotide phosphodiesterase family, PDE4 subfamily
  • 數(shù)據(jù)庫鏈接：

    STRING: 7227.FBpp0305507

    UniGene: Dm.4817



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