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  4. Recombinant Drosophila melanogaster Troponin I (wupA)

Recombinant Drosophila melanogaster Troponin I (wupA)

  • 中文名稱：
    黑腹果蠅wupA重組蛋白
  • 貨號：
    CSB-YP024013DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅wupA重組蛋白
  • 貨號：
    CSB-EP024013DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅wupA重組蛋白
  • 貨號：
    CSB-EP024013DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅wupA重組蛋白
  • 貨號：
    CSB-BP024013DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅wupA重組蛋白
  • 貨號：
    CSB-MP024013DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    wupA
  • Uniprot No.：
  • 別名：
    wupA; HDP; TnI; CG7178; Troponin I; Tn I; Protein heldup; Protein wings apart-A
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    2-269
  • 氨基酸序列
    ADDEKKAAA PAAAPAAAAK PAAPAAAPAA NGKAAPAANG KAAPAAAAAP AGPPKDPNDP KVKAEEAKKA KQAEIERKRA EVRKRMEEAS KAKKAKKGFM TPERKKKLRL LLRKKAAEEL KKEQERKAAE RRRIIEERCG SPRNLSDASE GELQEICEEY YERMYICEGQ KWDLEYEVRK KDWEINDLNA QVNDLRGKFV KPALKKVSKY ENKFAKLQKK AAEFNFRNQL KVVKKKEFTL EEEEKEKKPD WSKGKPGDAK VKEEVEAEA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Troponin I is the ATPase inhibitory subunit of troponin in the thin filament regulatory complex. Involved in the development and maintenance of muscle and nervous system. May also be involved in the cytoskeletal apparatus.
  • 基因功能參考文獻：
    1. Findings suggest that troponin-I (wupA) may be of therapeutic interest in certain types of cancer. PMID: 27437768
    2. Regulatory mutation fliH leads to reduced levels of troponin-I and muscle hypercontraction. PMID: 25747460
    3. In vitro motility of native thin filaments from Drosophila indirect flight muscles reveals that the held-up 2 TnI mutation affects calcium activation. PMID: 20658179
  • 蛋白家族：
    Troponin I family
  • 組織特異性：
    All isoforms are expressed in somatic muscle. Isoforms containing exon 6a1 (isoforms 1 and 2) are expressed in all muscles but highest expression is in abdominal muscle and splanchnic muscle of the gut. Isoforms containing exon 6b1 (isoforms 5, 6, 9 and 1
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG7178

    STRING: 7227.FBpp0074298

    UniGene: Dm.1717



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