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  4. Recombinant Drosophila melanogaster Steroid receptor seven-up, isoform A (svp), partial

Recombinant Drosophila melanogaster Steroid receptor seven-up, isoform A (svp), partial

  • 中文名稱：
    黑腹果蠅svp重組蛋白
  • 貨號：
    CSB-YP321439DLU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅svp重組蛋白
  • 貨號：
    CSB-EP321439DLU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅svp重組蛋白
  • 貨號：
    CSB-EP321439DLU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅svp重組蛋白
  • 貨號：
    CSB-BP321439DLU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅svp重組蛋白
  • 貨號：
    CSB-MP321439DLU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    svp
  • Uniprot No.：
  • 別名：
    svp; NR2F3; CG11502Steroid receptor seven-up; isoform A; Nuclear receptor subfamily 2 group F member 3; isoform A
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC-2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs).
  • 基因功能參考文獻：
    1. Authors propose that the Seven-up-initiated Imp/Syp gradients create coarse temporal windows within type II neuroblasts to pattern INPs, which subsequently undergo fine-tuned subtemporal patterning. PMID: 28434858
    2. A novel allele of svp was isolated. Expression analysis showed that svp is expressed in two distinct pulses in the embryonic NB5-6T lineage. PMID: 22071101
    3. Appropriate recruitment of the R3/R4 photoreceptor pair mediated by svp is a necessary prerequisite for the correct response of the ommatidial precluster to the Fz polarity signal. PMID: 9651479
    4. expression in combination with prospero and elav identifies progenitor cell types during sense-organ differentiation in the Drosophila antenna PMID: 12606283
    5. svp modifies the self-renewal stem cell program to allow chronological change of cell fates, thereby generating neuronal diversity. PMID: 15691762
    6. Results suggest that svp is required for the differentiation of Eve-positive pericardial cells and DA1 muscle founders and may have a role in EPC cell growth PMID: 16450585
    7. Enhancer of svp is initially activated by the NK homeodomain factor Tinman (Tin) via two conserved Tin binding sites. PMID: 17098220
    8. Normal patterning of alary muscles along the dorsal vessel was found to be a function of the Bithorax Complex genes abdominal-A (abd-A) and Ultrabithorax (Ubx) but not of the orphan nuclear receptor gene svp. PMID: 19272319

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Nuclear hormone receptor family, NR2 subfamily
  • 組織特異性：
    Expressed in several embryonic tissues; dorsal vessel, oenocyte and fat body. CNS expression is dynamic and confined to temporally restricted subsections of the NB lineage; expressed in many NB and GMCs, but only a small number of neurons.
  • 數據庫鏈接：

    STRING: 7227.FBpp0082035

    UniGene: Dm.20676



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