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  4. Recombinant Drosophila melanogaster Serine/threonine-protein kinase PAK mbt (mbt), partial

Recombinant Drosophila melanogaster Serine/threonine-protein kinase PAK mbt (mbt), partial

  • 中文名稱：
    黑腹果蠅mbt重組蛋白
  • 貨號：
    CSB-YP894288DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅mbt重組蛋白
  • 貨號：
    CSB-EP894288DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅mbt重組蛋白
  • 貨號：
    CSB-EP894288DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅mbt重組蛋白
  • 貨號：
    CSB-BP894288DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅mbt重組蛋白
  • 貨號：
    CSB-MP894288DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    mbt
  • Uniprot No.：
  • 別名：
    mbt; CG18582; Serine/threonine-protein kinase PAK mbt; EC 2.7.11.1; Protein mushroom bodies tiny; p21-activated kinase-related protein
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in neurogenesis of the adult central nervous system, and together with Cdc42, regulates photoreceptor cell morphogenesis. Phosphorylates exogenous substrates when activated by Cdc42.
  • 基因功能參考文獻：
    1. Pak4 regulates adherens junction accumulation. Pak4 promotes Par3 retention at the zonula adherens. PMID: 27052178
    2. Mbt regulates neuroblast number throughout postembryonic brain development. PMID: 23571212
    3. role for Mbt as a downstream effector of Cdc42 in photoreceptor cell morphogenesis PMID: 12490550
    4. Constitutive activation of Mbt not only disturbs the actin cytoskeleton but also affects adherens junction organisation indicating a requirement of the protein in cell adhesion dependent processes during photoreceptor cell differentiation. PMID: 17097274
    5. Activation of the human Mbt homologue PAK4 leads to anchorage-independent growth and provide a functional link between a PAK protein and the cadherin-catenin complex. PMID: 18636970

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  • 亞細胞定位：
    Cell junction, adherens junction. Cell membrane; Peripheral membrane protein. Note=Apical membrane sites of adherens junctions of developing photoreceptor cells.
  • 蛋白家族：
    Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
  • 組織特異性：
    Expressed in adult brain and eye. High levels detected in developing photoreceptor cells and future bristle cells, and lower levels in cone and pigment cells, as detected in third instar eye imaginal disks (at protein level).
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG18582

    STRING: 7227.FBpp0074060

    UniGene: Dm.4406



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