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Recombinant Drosophila melanogaster Serine/threonine-protein kinase N (Pkn), partial

  • 中文名稱:
    黑腹果蠅Pkn重組蛋白
  • 貨號:
    CSB-YP381778DLU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    黑腹果蠅Pkn重組蛋白
  • 貨號:
    CSB-EP381778DLU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    黑腹果蠅Pkn重組蛋白
  • 貨號:
    CSB-EP381778DLU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    黑腹果蠅Pkn重組蛋白
  • 貨號:
    CSB-BP381778DLU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    黑腹果蠅Pkn重組蛋白
  • 貨號:
    CSB-MP381778DLU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Pkn
  • Uniprot No.:
  • 別名:
    Pkn; Dpkn; CG2049; Serine/threonine-protein kinase N; EC 2.7.11.13; Protein kinase related to PKN
  • 種屬:
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Pkc-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. May play a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion and transcription activation signaling processes. Plays a role in regulating Rho-mediated dorsal closure during embryogenesis.
  • 基因功能參考文獻:
    1. polarity-induced spatiotemporal control of Rok and Pkn is important for unequal cortical expansion, ensuring correct cleavage furrow positioning and the establishment of physical asymmetry. PMID: 28712722
    2. The delorean phenotype, with its associated defects in wing morphology, provides evidence of a role for PKN in adult morphogenetic processes. PMID: 24531729
    3. Drosophila protein kinase N is a negative regulator of actin-myosin activity during oogenesis. PMID: 25131196
    4. identified a requirement for Pkn in wing morphogenesis, thereby revealing the first postembryonic function for Pkn PMID: 17507675
  • 亞細胞定位:
    Cytoplasm. Nucleus. Membrane. Cell projection, lamellipodium. Cytoplasm, cytoskeleton. Cleavage furrow. Midbody. Cell junction.
  • 蛋白家族:
    Protein kinase superfamily, Ser/Thr protein kinase family
  • 數(shù)據(jù)庫鏈接:

    KEGG: dme:Dmel_CG2049

    STRING: 7227.FBpp0111810

    UniGene: Dm.7964



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