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  4. Recombinant Drosophila melanogaster Protocadherin-like wing polarity protein stan (stan), partial

Recombinant Drosophila melanogaster Protocadherin-like wing polarity protein stan (stan), partial

  • 中文名稱：
    黑腹果蠅stan重組蛋白
  • 貨號：
    CSB-YP895571DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅stan重組蛋白
  • 貨號：
    CSB-EP895571DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅stan重組蛋白
  • 貨號：
    CSB-EP895571DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅stan重組蛋白
  • 貨號：
    CSB-BP895571DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅stan重組蛋白
  • 貨號：
    CSB-MP895571DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    stan
  • Uniprot No.：
  • 別名：
    stan; fmi; CG11895; Protocadherin-like wing polarity protein stan; Protein flamingo; Protein starry night
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in the fz signaling pathway that controls wing tissue polarity. Also mediates homophilic cell adhesion. May play a role in initiating prehair morphogenesis. May play a critical role in tissue polarity and in formation of normal dendrite fields. During planar cell polarity, stabilizes asymmetric PCP domains together with ATP6AP2.
  • 基因功能參考文獻：
    1. microRNA-9a regulates dendrite growth through cadherin protein Flamingo-G protein Galphaq signaling in Drosophila sensory neurons PMID: 26016469
    2. Fmi and Gogo function downstream of Otd in retina. PMID: 26114289
    3. The planar cell polarity gene prickle interacts with flamingo in regulating sensory axon advance at a key choice point - the transition between the peripheral nervous system and the central nervous system. PMID: 21827745
    4. Espinas (Esn), binds to an intracellular juxtamembrane domain of Flamingo (Fmi), and that this Fmi-Esn interplay elicits repulsion between dendritic branches of Drosophila sensory neurons PMID: 21937715
    5. Data suggest that Gogo acts as a functional partner of Fmi for R8 photoreceptor axon targeting and that the dynamic regulation of their interaction specifies synaptic-layer selection of photoreceptors. PMID: 21317905
    6. The atypical cadherin Flamingo (Fmi) plays critical, but distinct, roles in distinct fate specification of photoreceptors R3 and R4. PMID: 12015972
    7. Flamingo plays a role in early neuronal differentiation and exerts specific effects on dendrites and axons PMID: 12074553
    8. Autonomously required for the establishment of ommatidial polarity. PMID: 12642492
    9. Flamingo occurs in retinal growth cones. Loss of Flamingo function in retinal cells disrupts the local pattern of synaptic terminals in the medulla; Flamingo is transiently expressed in retinal axons as they enter the target region. PMID: 12754514
    10. Flamingo expresses two differentially spliced RNAs in wing imaginal discs, which encode two isoforms of the atypical cadherin Flamingo. PMID: 17304516
    11. Atypical cadherin Flamingo functions as a short-range, homophilic signal, passing between specific R cell growth cones to influence postsynaptic targeting. PMID: 18400160
    12. Study provides evidence that Fmi functions instructively to mediate Fz-Vang intercellular signal relay, recruiting Fz and Vang to opposite sides of cell boundaries. PMID: 18555784
    13. Flamingo protein binds preferentially to the Fz:Dsh complex and controls asymmetric localization of polarity proteins in pupal wing cells. PMID: 18804371
    14. Results suggest that Flamingo mediates an interaction between sensory neuron growth cones and intermediate targets, which is required for continued axon advance. PMID: 19146847

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  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Apical cell membrane.
  • 蛋白家族：
    G-protein coupled receptor 2 family
  • 組織特異性：
    In the pupal wing, expressed at relatively even levels in all regions. Abundant in 6-9 hours embryos. Expressed at higher levels in pupae than larvae.
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG11895

    STRING: 7227.FBpp0303451

    UniGene: Dm.4360



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