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  4. Recombinant Drosophila melanogaster Protein takeout (to)

Recombinant Drosophila melanogaster Protein takeout (to)

  • 中文名稱：
    黑腹果蠅to重組蛋白
  • 貨號：
    CSB-YP896068DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅to重組蛋白
  • 貨號：
    CSB-EP896068DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅to重組蛋白
  • 貨號：
    CSB-EP896068DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅to重組蛋白
  • 貨號：
    CSB-BP896068DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅to重組蛋白
  • 貨號：
    CSB-MP896068DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    to
  • Uniprot No.：
  • 別名：
    to; CG11853; Protein takeout
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    19-249
  • 氨基酸序列
    KF PEDPKPCKYG DGECIMKLCN TLFSENSAEG DPGLNLMQLD PLKVDRMVIS QGESSSPVGI TLTFTDNLLY GIKDQRIVKV KGFGRDLTAK HEVKIVTKTF SLVGPYNIQG KVLILPISGT GQSNMTMVNV RAIVSFSGKP LVKNGETYLD VTDLKITMKP ESSHYHFSNL FNGDKALGDN MNVFLNENSE AIYKETAKAI DRSFGKLYLG VVKGVFSKLP YAKFFADES
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Participates in a novel circadian output pathway that conveys temporal and food status information to feeding-relevant metabolisms and activities. Involved in male courtship behavior. In the brain-associated fat body, transcription is enhanced by the dsx and fru male-specific isoforms and repressed by the dsx female-specific isoform.
  • 基因功能參考文獻：
    1. takeout-dependent longevity is associated with altered Juvenile Hormone signaling PMID: 22940452
    2. We show that a number of genes in the takeout gene family show male-biased expression in D. melanogaster, largely in non-reproductive tissues. PMID: 22020223
    3. Data show that takeout levels are low in flies with reduced Pdp1epsilon and high in flies with increased amounts of Pdp1epsilon. PMID: 20133786
    4. A loss-of-function mutation in the takeout gene reduces male courtship and synergizes with fruitless mutations, suggesting that takeout plays a redundant role with other fru-dependent factors involved in male mating behavior PMID: 12435630
    5. takeout plays a central role as a feeding regulator and may act by modulating the circulating Juvenile Hormone level. PMID: 17401125
    6. Drosophila Takeout gene expression varied with diurnal or circadian rhythms. These findings suggest that Apis mellifera GB19811 is not an ortholog of Takeout. PMID: 17550825

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  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    TO family
  • 組織特異性：
    Expression is largely restricted to head, with limited expression detectable in cardia and crop. In entrained individuals, expression is observed in the brain cortex (region between optic lobe and central complex), photoreceptors and antennae. In asynchro
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG11853

    STRING: 7227.FBpp0084185

    UniGene: Dm.2360



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