在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Drosophila melanogaster Protein prickle (pk), partial

  • 中文名稱:
    黑腹果蠅pk重組蛋白
  • 貨號:
    CSB-YP381174DLU
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    黑腹果蠅pk重組蛋白
  • 貨號:
    CSB-EP381174DLU
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    黑腹果蠅pk重組蛋白
  • 貨號:
    CSB-EP381174DLU-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    黑腹果蠅pk重組蛋白
  • 貨號:
    CSB-BP381174DLU
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    黑腹果蠅pk重組蛋白
  • 貨號:
    CSB-MP381174DLU
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    pk
  • Uniprot No.:
  • 別名:
    pk; CG11084; Protein prickle; Protein spiny legs
  • 種屬:
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts in a planar cell polarity (PCP) complex; polarization along the apical/basal axis of epithelial cells. Correct expression of the alternative isoforms is required for PCP signaling in imaginal disks. PCP signaling in the wing disk requires the receptor fz and the cytoplasmic proteins dsh and pk. These act in a feedback loop leading to activation of the jnk cascade and subsequent polarized arrangement of hairs and bristles. Dgo and pk compete with one another for dsh binding, thereby modulating fz dsh activity and ensuring tight control over fz PCP signaling. Vang, stan and pk function together to regulate the establishment of tissue polarity in the adult eye.
  • 基因功能參考文獻:
    1. We find that the E3 ubiquitin ligase complex Cullin1(Cul1)/SkpA/Supernumerary limbs(Slimb) regulates the stability of one of the peripheral membrane components, Prickle (Pk). PMID: 25996914
    2. Pk and Sple form different complexes with distinct subcellular localizations in the eye and wing. PMID: 24998533
    3. Fat and Core planar cell polarity (PCP) pathways patterns change during morphogenesis, undergoing phases of coupling and uncoupling that are regulated by antagonistic Core PCP protein isoforms Prickle and Spiny-legs. PMID: 25201685
    4. These data reveal a previously unidentified pathway in the pathophysiology of seizure disorders and provide evidence for a more generalized cellular mechanism whereby Prickle mediates polarity by influencing microtubule-mediated transport. PMID: 25024231
    5. Alternative Prickle (Pk-Sple) protein isoforms control the polarity of microtubule network. PMID: 25005476
    6. Pk mediates feedback amplification to generate asymmetric planar cell polarity signaling in Drosophila. PMID: 12015986
    7. Prickle localization is influenced by Strabismus function. PMID: 12642492
    8. the initial membrane association of Diego depends on Fz, and that Diego physically interacts with Strabismus and Pk through its Ankyrin repeats PMID: 15306567
    9. Prickle competitively binds with Dishevelled and thereby modulating Frizzled/Dishevelled activity. PMID: 15937478
    10. Pk(Pk) is sufficient to mediate the intercellular feedback signalling. Significantly, Pk(Pk) but not Pk(Sple) is required for hexagonal cell packing in the pupal wing. PMID: 19028485
    11. analysis of structural and membrane binding properties of the prickle PET domain PMID: 19053268

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Prickle / espinas / testin family
  • 組織特異性:
    Expressed in the wing, leg and eye imaginal disks. Expressed within the photoreceptors of the eye.
  • 數據庫鏈接:

    KEGG: dme:Dmel_CG11084

    STRING: 7227.FBpp0088115

    UniGene: Dm.3470



主站蜘蛛池模板: 国产精品天堂avav在线| 伊人久久大香线蕉av最新| 另类亚洲综合区图片小说区| 暴力强奷在线播放无码| 一 级 黄 色 片免费网站| 西西人体444www大胆无码视频| 久青草影院在线观看国产| 影音先锋啪啪av资源网站| 四虎国产精品永久在线观看| 久久久亚洲精华液精华液精华液| 青青草国产免费久久久| 日本久久久久久级做爰片| 又大又粗弄得我出好多水| 色综合色综合久久综合频道88| 亚洲精品宾馆在线精品酒店| 涩欲国产一区二区三区四区| 欧美精品高清在线观看| 国产欧美一区二区精品性色| 中文字幕乱码无码人妻系列蜜桃| 黄网站色视频免费观看| 日本乱码伦午夜福利在线| 一本精品中文字幕在线| 国内大量揄拍人妻在线视频| 国产福利酱国产一区二区| 99久久久无码国产精品9| 久久亚洲国产成人影院| 日韩人妻无码精品系列专区| av天堂亚洲区无码先锋影音| 苍井空张开腿实干12次| 忍着娇喘人妻被中出中文字幕| 又色又爽又黄的美女裸体网站 | 三叶草欧洲码在线| 免费无码av片在线观看国产| 人妻插b视频一区二区三区| 国产精品白浆无码流出| 猫咪www免费人成网站无码| 天堂va视频一区二区| 国产午夜亚洲精品国产成人小说 | 成人免费无码大片a毛片户外| 在线看亚洲十八禁网站| 久青草无码视频在线观看|