在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Drosophila melanogaster Protein ovo (ovo), partial

  • 中文名稱:
    黑腹果蠅ovo重組蛋白
  • 貨號:
    CSB-YP343943DLU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    黑腹果蠅ovo重組蛋白
  • 貨號:
    CSB-EP343943DLU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    黑腹果蠅ovo重組蛋白
  • 貨號:
    CSB-EP343943DLU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    黑腹果蠅ovo重組蛋白
  • 貨號:
    CSB-BP343943DLU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    黑腹果蠅ovo重組蛋白
  • 貨號:
    CSB-MP343943DLU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ovo
  • Uniprot No.:
  • 別名:
    ovo; svb; CG6824Transcriptional regulator ovo; Transcriptional repressor shavenbaby; Transcriptional repressor svb) [Cleaved into: Transcriptional activator shavenbaby; Transcriptional activator svb)]
  • 種屬:
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Transcriptional regulator with essential functions in the germline and soma. Plays an essential role in regulating the formation of apical cell extensions such as denticles and aristae, and initiating cytoskeletal remodeling during epidermal differentiation.; Transcriptional repressor which functions in postembryonic development. The full-length unprocessed form acts as a transcriptional repressor (Transcriptional repressor svb).; Transcriptional activator which initiates trichome development and also promotes tarsal joint development. Has an essential somatic role regulating the tal-dependent formation of trichomes, and initiating cytoskeletal remodeling during epidermal differentiation. Function with SoxN is required for correct denticle morphogenesis on the embryonic epidermis. SoxN and svb appear to act both independently and in conjunction with each other to activate certain genes involved in denticle morphogenesis; Svb appears to be involved in regulating denticle length whereas SoxN regulates the denticle base circumference. Also functions in the development of other apical cell extensions such as bristles. Also has an important role in tarsal joint development, repressing expression of the N ligand Dl and defining its signaling boundary.; Transcriptional repressor which is specifically involved in female germline development, where it functions antagonistically to isoform D. Negatively regulates expression of otu and may also have autoregulatory activity. Negatively regulates expression of piwi in the primordial germ cells (PGCs).; Transcriptional activator which is specifically involved in female germline development, where it functions antagonistically to isoform C. Necessary and sufficient for normal oogenesis. Required in the primordial germ cells (PGCs) for normal development of male and female germline cells. Plays a role in germline sex determination. Binds the promoter DNA and positively regulates the transcription of the otu gene in a stage-specific manner. May have autoregulatory activity.
  • 基因功能參考文獻:
    1. Co-expressing ectopic SoxN with svb rescued diverse denticle morphologies. Conversely, removing SoxN activity eliminated the residual denticles found in svb mutant embryos. Furthermore, several known Svb target genes are also activated by SoxN, and we have discovered two novel target genes of SoxN that are expressed in denticle-producing cells and that are regulated independently of Svb. PMID: 28506986
    2. Report the high-resolution functional dissection of a robust enhancer of the shavenbaby gene that has contributed to morphological evolution. We found that robustness is encoded by many binding sites for the transcriptional activator Arrowhead and that, during evolution, some of these activator sites were lost, weakening enhancer activity. PMID: 27840106
    3. Hox protein Ultrabithorax (Ubx) in complex with its cofactor Extradenticle (Exd) bound specifically to clusters of very low affinity sites in enhancers of the shavenbaby gene of Drosophila. These low affinity sites conferred specificity for Ubx binding in vivo, but multiple clustered sites were required for robust expression when embryos developed in variable environments. PMID: 25557079
    4. Multiple shavenbaby enhancers drive overlapping patterns of expression in the embryo. PMID: 24218640
    5. study shows peptides of 11 to 32 amino acids encoded by polished rice(pri)sORF gene control epidermal differentiation by modifying Shavenbaby (Svb); Pri peptides trigger amino-terminal truncation of Svb which converts Svb from a repressor to an activator PMID: 20647469
    6. ovo-B is strongly expressed in the 2X germ cells in either a male or a female soma (ovo-B) PMID: 11861560
    7. genetic and gene expression data show regulatory changes of the shavenbaby/ovo (svb/ovo) gene underlie independent cases of morphological convergence PMID: 12931187
    8. shavenbaby governs an evolutionarily conserved developmental module consisting of a set of genes collectively responsible for trichome formation PMID: 16933974
    9. SoxN is necessary and sufficient to cell-autonomously direct the expression of svb. PMID: 17611224
    10. identification of three distinct svb enhancers from D. melanogaster driving reporter gene expression in partly overlapping patterns that together recapitulate endogenous svb expression. PMID: 17632547
    11. Results show that the embryonic expression of dsc73 requires Shavenbaby, a transcription factor regulating cuticle formation. PMID: 18351665

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.; [Transcriptional activator shavenbaby]: Nucleus, nucleoplasm.; [Isoform B]: Nucleus.; [Isoform C]: Nucleus.; [Isoform D]: Cytoplasm. Nucleus. Nucleus, nucleoplasm.
  • 數據庫鏈接:

    KEGG: dme:Dmel_CG6824

    STRING: 7227.FBpp0291128

    UniGene: Dm.1677



主站蜘蛛池模板: 国产后入清纯学生妹| 国产又色又爽又刺激在线播放 | 无套内射在线无码播放| 双腿张开被9个黑人调教影片 | 国产成人综合久久久久久| 欧美 日产 国产在线观看| 日日碰狠狠添天天爽五月婷| 亚洲爆乳精品无码一区二区| 最爽无遮挡行房视频| 国产精品国产av片国产| 肉体裸交137日本大胆摄影| 亚洲熟妇av一区二区三区漫画| 欧美高清freexxxx性| 国产又黄又潮娇喘视频在线观看 | 久久亚洲春色中文字幕久久久 | 在线精品国精品国产尤物| 99e热久久免费精品首页| 成人欧美一区二区三区的电影| 国产av激情久久无码天堂 | 欧美亚洲日韩国产综合电影| 久久亚洲精品人成综合网| 亚洲色无码中文字幕yy51999| 亚洲 日韩 欧美 成人 在线观看| 欧洲一卡2卡3卡4卡国产| 久久99精品国产免费观观| 免费大片黄在线观看| 国产69精品久久久久乱码免费 | 国产成人精品一区二区三区视频| 国产亚洲欧美另类一区二区| 99久久国产综合精品女图图等你 | 99国产揄拍国产精品人妻| 性欧美大战久久久久久久久| 国产猛男猛女超爽免费视频| 亚洲国产欧美在线看片一国产| 亚洲日本一区二区三区在线| 国产在线 | 中文| 日本熟妇浓密毛毛多| 男人猛躁进女人免费播放| 欧美一区二区三区成人久久片| 日韩精品一区二区三区vr| 久久久肥妇熟女ⅹxxx毛片|