Recombinant Drosophila melanogaster Protein NPC2 homolog (Npc2a)

中文名稱：

黑腹果蠅Npc2a重組蛋白
貨號：

CSB-YP893313DLU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

黑腹果蠅Npc2a重組蛋白
貨號：

CSB-EP893313DLU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

黑腹果蠅Npc2a重組蛋白
貨號：

CSB-EP893313DLU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

黑腹果蠅Npc2a重組蛋白
貨號：

CSB-BP893313DLU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

黑腹果蠅Npc2a重組蛋白
貨號：

CSB-MP893313DLU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Npc2a
Uniprot No.：

Q9VQ62
別名：

Npc2a; NPC2; CG7291; NPC intracellular cholesterol transporter 2 homolog a; Niemann Pick type C2 protein homolog
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長度：

Full Length of Mature Protein
表達區域：

17-148
氨基酸序列

GALE FSDCGSKTGK FTRVAIEGCD TTKAECILKR NTTVSFSIDF ALAEEATAVK TVVHGKVLGI EMPFPLANPD ACVDSGLKCP LEKDESYRYT ATLPVLRSYP KVSVLVKWEL QDQDGADIIC VEIPAKIQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Functions redundantly with Npc2b in regulating sterol homeostasis and ecdysteroid biosynthesis, probably by controlling the availability of sterol substrate.
基因功能參考文獻：
1. may play a role in the immune deficiency pathway PMID: 22580186
2. Data suggest that npc2a functions redundantly with npc2b in regulating sterol homeostasis and ecdysteroid biosynthesis, probably by controlling the availability of sterol substrate. PMID: 17804599
亞細胞定位：

Secreted.
蛋白家族：

NPC2 family
組織特異性：

Broadly expressed with a higher level of expression in many tissues, including midgut, salivary gland and ventral nerve cord.
數據庫鏈接：

KEGG: dme:Dmel_CG7291

STRING: 7227.FBpp0077492

UniGene: Dm.7263