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  4. Recombinant Drosophila melanogaster Nucleosomal histone kinase 1 (ball), partial

Recombinant Drosophila melanogaster Nucleosomal histone kinase 1 (ball), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster Nucleosomal histone kinase 1(ball) ,partial
  • 貨號：
    CSB-YP762561DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Nucleosomal histone kinase 1(ball) ,partial
  • 貨號：
    CSB-EP762561DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Nucleosomal histone kinase 1(ball) ,partial
  • 貨號：
    CSB-EP762561DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Nucleosomal histone kinase 1(ball) ,partial
  • 貨號：
    CSB-BP762561DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Nucleosomal histone kinase 1(ball) ,partial
  • 貨號：
    CSB-MP762561DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ball
  • Uniprot No.：
  • 別名：
    ball; ballchen; nhk-1; CG6386; Nucleosomal histone kinase 1; EC 2.7.11.1; Protein baellchen
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Serine/threonine-protein kinase involved in somatic mitosis and female meiosis. Required for spindle organization in mitosis, and for the establishment or maintenance of meiosis-specific chromosomal configurations, including the prophase I karyosome and the metaphase I spindle. Specifically phosphorylates nucleosomal H2A on 'Thr-119'. Required for the development and organization of indirect flight muscle sarcomeres by regulating the formation of M line and H zone and the correct assembly of thick and thin filaments in the sarcomere.
  • 基因功能參考文獻(xiàn)：
    1. NHK-1 in chromosome condensation phosphorylates Barrier-to-autointegration factor and suppress its activity in linking chromosomes to nuclear envelope proteins and is important for chromosome condensation during mitosis as well as in oocytes. PMID: 25501812
    2. Data suggest that NHK-1 is a crucial regulator of meiosis and that the meiotic checkpoint suppresses NHK-1 activity to prevent oocyte nuclear reorganisation until DNA breaks are repaired. PMID: 21060809
    3. NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster PMID: 16301329
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Chromosome. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere, M line.
  • 蛋白家族：
    Protein kinase superfamily, CK1 Ser/Thr protein kinase family, VRK subfamily
  • 組織特異性：
    Expressed in ovaries (at protein level). Expressed in indirect flight muscle (IFM) (at protein level).
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG6386

    STRING: 7227.FBpp0084465

    UniGene: Dm.1346



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