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  4. Recombinant Drosophila melanogaster Nuclear RNA export factor 1 (sbr), partial

Recombinant Drosophila melanogaster Nuclear RNA export factor 1 (sbr), partial

  • 中文名稱：
    黑腹果蠅sbr重組蛋白
  • 貨號：
    CSB-YP016218DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅sbr重組蛋白
  • 貨號：
    CSB-EP016218DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅sbr重組蛋白
  • 貨號：
    CSB-EP016218DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅sbr重組蛋白
  • 貨號：
    CSB-BP016218DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅sbr重組蛋白
  • 貨號：
    CSB-MP016218DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    sbr
  • Uniprot No.：
  • 別名：
    sbr; nxf1; CG1664; Nuclear RNA export factor 1; Protein small bristles; DmNXF1; Protein tip-associating
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm. In ovarian follicle cells, plays a role in transposable element silencing regulation by enabling the nuclear export of flamenco (flam) transcripts and subsequent piRNA biogenesis.
  • 基因功能參考文獻(xiàn)：
    1. we show that the Dm NXF1 (SBR) protein is present not only in the nucleus but also in the cytoplasm PMID: 27389771
    2. data indicate that origin recognition complex depletion affects the Nxf1 association with the mRNP complex. PMID: 27016737
    3. sbr12 deletion and short testis-specific isoforms of SBR cause male sterility. PMID: 26621383
    4. For SBR protein we have shown the localization not only in the nucleus, but in the cytoplasm marking of characteristic cytoplasmic structures. PMID: 26349247
    5. Dm NXF1 (SBR) protein is present in considerable amounts at all stages of the spermatogenesis. PMID: 20799623
    6. Alternative transcripts expressed by small bristles, the Drosophila melanogaster nxf1 gene PMID: 20214956
    7. demonstrate that the SBR(5) mutant allele is a deletion of 492 nucleotides that removes 146 amino acids in the mutant SBR(5) protein. PMID: 19779841
    8. The frequency of abnormal chromosome sets in the offspring of male carriers of the sbr10 mutation is about two times higher than in the offspring of males without this mutation. PMID: 18069342

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  • 亞細(xì)胞定位：
    Nucleus, nucleoplasm. Cytoplasm. Nucleus envelope.
  • 蛋白家族：
    NXF family
  • 組織特異性：
    Expressed ubiquitously.
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG1664

    STRING: 7227.FBpp0073267

    UniGene: Dm.1645



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