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  4. Recombinant Drosophila melanogaster Neutral ceramidase (CDase), partial

Recombinant Drosophila melanogaster Neutral ceramidase (CDase), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster Neutral ceramidase(CDase) ,partial
  • 貨號：
    CSB-YP892700DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Neutral ceramidase(CDase) ,partial
  • 貨號：
    CSB-EP892700DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Neutral ceramidase(CDase) ,partial
  • 貨號：
    CSB-EP892700DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Neutral ceramidase(CDase) ,partial
  • 貨號：
    CSB-BP892700DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Neutral ceramidase(CDase) ,partial
  • 貨號：
    CSB-MP892700DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CDase
  • Uniprot No.：
  • 別名：
    CDase; slab; CG1471; Neutral ceramidase; N-CDase; NCDase; EC 3.5.1.23; Neutral N-acylsphingosine amidohydrolase; Neutral acylsphingosine deacylase; Slug-a-bed protein
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-7.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Regulates synaptic vesicle exocytosis and trafficking by controlling presynaptic terminal sphingolipid composition.
  • 基因功能參考文獻：
    1. findings show the neutral ceramidase gene CDase encodes the protein that is responsible for all measurable ceramidase activity in Drosophila; studies show strong genetic interaction of Bwa with CDase and the ceramide kinase gene PMID: 21148295
    2. Data report the molecular cloning and characterization of the Drosophila neutral ceramidase. PMID: 12153720
    3. SLAB ceramidase function controls presynaptic terminal sphingolipid composition to regulate vesicle fusion and trafficking, and thus the strength and reliability of synaptic transmission PMID: 15356190
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Neutral ceramidase family
  • 組織特異性：
    Widely expressed in different tissues but enriched in neurons at all stages of development.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG1471

    STRING: 7227.FBpp0303775

    UniGene: Dm.16294



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