在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Drosophila melanogaster Neurogenic locus protein delta (Dl), partial

Recombinant Drosophila melanogaster Neurogenic locus protein delta (Dl), partial

  • 中文名稱：
    黑腹果蠅Dl重組蛋白
  • 貨號(hào)：
    CSB-YP318005DLU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Dl重組蛋白
  • 貨號(hào)：
    CSB-EP318005DLU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Dl重組蛋白
  • 貨號(hào)：
    CSB-EP318005DLU-B
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Dl重組蛋白
  • 貨號(hào)：
    CSB-BP318005DLU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Dl重組蛋白
  • 貨號(hào)：
    CSB-MP318005DLU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Dl
  • Uniprot No.：
  • 別名：
    Dl; CG3619; Neurogenic locus protein delta
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Acts as a ligand for Notch (N) receptor. Essential for proper differentiation of ectoderm. Dl is required for the correct separation of neural and epidermal cell lineages. Fringe (fng) acts in the Golgi to determine the type of O-linked fucose on the EGF modules in N, altering the ability of N to bind with Delta (Dl). O-fut1 also has a role in modulating the interaction.
  • 基因功能參考文獻(xiàn)：
    1. A new paramutation-like example at the Delta gene of Drosophila has been described. PMID: 28355214
    2. Binding of Notch to ligands of the Delta/DLL and Serrate/JAG families from neighboring cells leads to activation of the signaling pathway and is called trans-activation PMID: 28394891
    3. miR-124 plays neuroprotective roles in Alzheimer's disease Drosophila by targeting Delta in Notch signaling pathway. PMID: 26592243
    4. Notch activation by odorants depends on the Delta/Serrate/Lag2 ligand Delta in select olfactory receptor neurons. PMID: 21315258
    5. Differential Vegfr levels affect tip selection only in the presence of a functional Notch system by modulating the expression of the ligand Dll4. PMID: 20871601
    6. Delta is endocytosed in a Neuralized-dependent manner from the basolateral membrane. PMID: 20410139
    7. Dl transcription and protein levels did correlate with altered N signaling in mutant genotypes. PMID: 9651468
    8. results show that sna is required for the Neur-dependent endocytosis of Delta in the mesoderm, suggesting that Sna regulates the ability of mesodermal cells to signal and activate Notch receptors PMID: 12632175
    9. Delta is requiredfor the positioning of oocyte in the adjacent younger cyst. PMID: 14536057
    10. extension of planar filopodia is promoted by Delta; experimental suppression reduces Notch signalling in distant cells and increases bristle density in large proneural groups, showing these membrane specializations mediate long-range lateral inhibition PMID: 14654840
    11. two previously detected genotype/phenotype associations between bristle number and variants in the introns of Delta cannot be explained by linkage disequilibrium between these variants and nearby nonsynonymous variants PMID: 15020426
    12. Faf plays a role similar to that of Neur in the Delta signaling cells; by deubiquitinating Lqf, which enhances the efficiency of Delta internalization, Faf stimulates Delta signaling PMID: 15469967
    13. Proteolytic cleavage of Dl by Kul represents a general mechanism for refining and maintaining the asymmetric distribution of Dl PMID: 15576412
    14. Altogether, these data support a model whereby proteolysis can modulate Delta ligand activity independently of endocytosis. PMID: 16487968
    15. the Hox genes, Sex combs reduced (Scr) and Ultrabithorax (Ubx), establish differential expression of the proneural gene achaete (ac) by modifying expression of the ac prepattern regulator, Delta (Dl), in T1 and T3 legs, respectively PMID: 17107776
    16. Fringe sensitizes Notch on glia to axon-derived Delta PMID: 17215308
    17. Delta loss-of-function alleles dominantly suppress Msk gain-of-function phenotypes in the developing wing. PMID: 17628519
    18. HNT functions in the determined R1/R6 precursor cells to allow Delta transcription to reach high enough levels at the right time to induce the cone-cell determinants Prospero and D-Pax2 in neighboring cells PMID: 19234063
    19. In R1/R6/R7 photoreceptor precursors, unidirectional signaling depends on Dl's ability to inhibit Notch within the same cell. Loss of Dl-mediated cis-inhibition reverses the direction of lateral signaling. PMID: 19631544
    20. suggests that within a NB lineage Delta is dispensable for sibling cell fate specification PMID: 19782677

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Detected in all areas with neurogenic abilities, for example the neurogenic ectoderm and the primordia of the sense organs. Later expression is restricted to those cells that have adopted a neural fate.
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: dme:Dmel_CG3619

    STRING: 7227.FBpp0083153

    UniGene: Dm.7687



主站蜘蛛池模板： 免费夜色污私人影院在线观看| 人人入人人爱| 欧美变态另类刺激| 伊人久久综合成人网| 久久大蕉香蕉免费| 色噜噜噜亚洲男人的天堂| 人人妻人人澡人人爽人人精品电影| 免费人成视频在线| 精品无码中文字幕在线| 亚洲妇女自偷自偷图片| 亚洲熟女乱色一区二区三区| 一性一交一口添一摸视频| 亚洲va在线va天堂xx xx| 国产精品极品在线拍| 婷婷色婷婷开心五月四房播播| 老司机午夜免费精品视频| 99久久无色码中文字幕人妻| 国产精品久久久久无码av1| 男女猛烈xx00免费视频试看| 亚洲精品无人区| 亚洲精品午夜理伦不卡在线观看| 午夜dv内射一区二区| 欧美成人看片一区二区三区尤物| 国产α片免费观看在线人| 欧美不卡视频一区发布| 麻豆传传媒久久久爱| 无遮无挡三级动态图| 成人性欧美丨区二区三区| 色欲av亚洲一区无码少妇| 中国女人内谢69xxxxxa片| 午夜亚洲www湿好大| 中文字幕人妻偷伦在线视频| 欧美大胆少妇bbw| 女人被做到高潮免费视频| 亚洲人成电影免费观看在线看 | 99热久久这里只有精品| 伊人无码精品久久一区二区| 无人区乱码区1卡2卡三卡网站| 奇米影视第四色首页| 亚洲色大成网站在线| 一区二区三区在线 | 日|