在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Drosophila melanogaster Lysine-specific demethylase lid (lid), partial

Recombinant Drosophila melanogaster Lysine-specific demethylase lid (lid), partial

  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-YP895166DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-EP895166DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-EP895166DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-BP895166DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-MP895166DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    lid
  • Uniprot No.：
  • 別名：
    lid; CG9088; Lysine-specific demethylase lid; EC 1.14.11.-; Histone demethylase lid; Jumonji/ARID domain-containing protein lid; Protein little imaginal disks; Retinoblastoma-binding protein 2 homolog
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Specifically demethylates trimethylated H3 'Lys-4'. Required for the correct regulation of homeotic genes during development. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. Regulates the expression of clock-controlled genes including tim, per and cry.
  • 基因功能參考文獻：
    1. However, for the N terminal region harboring both a PHD and an ARID finger, Lid anchors to the NuMat via both protein-protein and protein-DNA interactions. The association of JmjC domain with NuMat is the first report of the association of a demethylase domain with NuMat suggesting that Lid, a demethylase, being part of NuMat might be involved in regulating the chromatin dynamics via its NuMat association. PMID: 30207309
    2. Analyses reveal KDM5 as a key regulator of larval growth and offer an invaluable tool for defining the biological activities of KDM5 family proteins. PMID: 29764901
    3. Therefore Kdm5/Lid controls chromatin architecture in meiotic prophase I oocytes independently of its demethylase activity. PMID: 27494704
    4. we demonstrate a direct, critical role for KDM5 in the activation of genes required for the integrity and functioning of mitochondria PMID: 26673323
    5. KDM5 interacts with Foxo to modulate cellular levels of oxidative stress.KDM5 interacts with the lysine deacetylase HDAC4 to promote Foxo deacetylation, which affects Foxo DNA binding. PMID: 25329053
    6. dKDM5/LID regulates Drosophila hematopoietic development PMID: 26183107
    7. The results indicate that, at developmental genes, dKDM5/LID and ASH2 coordinately regulate H3K4me3 at the transcription-start site and that this dynamic regulation contributes to transcription. PMID: 22904080
    8. These findings highlight the importance of Lid function in the regulated removal and recognition of histone H3 lysine 4 during development. PMID: 21124823
    9. Lid knockdown using RNA interference results in a specific genome-wide increase in histone lysine methylation levels without affecting other patterns of H3 methylation, and results in an altered distribution of the chromo-helicase protein Chd1. PMID: 17351630
    10. Drosophila melanogaster protein 'little imaginal discs' (Lid), a JmjC domain-containing trithorax group protein, can demethylate histone H3trimethyl-Lys4. PMID: 17351631
    11. The finding that Lid antagonizes Rpd3 function provides an explanation for the genetic classification of Lid as a positive transcription regulator. PMID: 19114561

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    JARID1 histone demethylase family
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG9088

    STRING: 7227.FBpp0297914

    UniGene: Dm.2779



主站蜘蛛池模板： 国产男女无遮挡猛进猛出| 天堂中文在线www天堂在线| 中文字幕人乱码中文字幕| 2024av天堂手机在线观看| 国产免费一区二区三区免费视频 | 欧美xxxx做受欧美| 国内精品九九久久久精品| 18禁超污无遮挡无码网址| 日韩精品久久久久久免费| 亚洲精品乱码久久久久久日本| 久久婷婷色香五月综合缴缴情| 国产精品视频观看裸模| 色综合久久久无码中文字幕波多 | 精品动漫一区二区无遮挡| 色婷婷美国农夫综合激情亚洲| 中文字幕乱码无码人妻系列蜜桃 | 欧洲国产精品无码专区影院 | 亚洲乱码日产精品bd在线观看 | 久久国产精品2020免费| 国产无吗一区二区三区在线欢| 无码人妻精品一区二区三区99不卡| 国产精品白浆在线观看免费| 中美日韩毛片免费播放 | 国内免费视频成人精品| 拍摄av现场失控高潮数次| 国产女同疯狂作爱系列| 国精品无码av人妻受辱系| 久久久国产乱子伦精品| 亚洲精品一区二区久久| 久久亚洲精品高潮综合色a片| 高清同性男毛片| 国产成人精品一区二区三区免费| av无码久久久久久不卡网站| 国产免费又色又爽又黄软件| 亚洲精品v日韩精品| 国产精品亲子乱子伦xxxx裸| 亚洲性无码一区二区三区| 日韩放荡少妇无码视频| av在线播放日韩亚洲欧| 欧美阿v天堂视频在99线| 色综合久久婷婷五月|