在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Drosophila melanogaster Lysine-specific demethylase lid (lid), partial

Recombinant Drosophila melanogaster Lysine-specific demethylase lid (lid), partial

  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-YP895166DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-EP895166DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-EP895166DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-BP895166DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅lid重組蛋白
  • 貨號：
    CSB-MP895166DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    lid
  • Uniprot No.：
  • 別名：
    lid; CG9088; Lysine-specific demethylase lid; EC 1.14.11.-; Histone demethylase lid; Jumonji/ARID domain-containing protein lid; Protein little imaginal disks; Retinoblastoma-binding protein 2 homolog
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Specifically demethylates trimethylated H3 'Lys-4'. Required for the correct regulation of homeotic genes during development. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. Regulates the expression of clock-controlled genes including tim, per and cry.
  • 基因功能參考文獻：
    1. However, for the N terminal region harboring both a PHD and an ARID finger, Lid anchors to the NuMat via both protein-protein and protein-DNA interactions. The association of JmjC domain with NuMat is the first report of the association of a demethylase domain with NuMat suggesting that Lid, a demethylase, being part of NuMat might be involved in regulating the chromatin dynamics via its NuMat association. PMID: 30207309
    2. Analyses reveal KDM5 as a key regulator of larval growth and offer an invaluable tool for defining the biological activities of KDM5 family proteins. PMID: 29764901
    3. Therefore Kdm5/Lid controls chromatin architecture in meiotic prophase I oocytes independently of its demethylase activity. PMID: 27494704
    4. we demonstrate a direct, critical role for KDM5 in the activation of genes required for the integrity and functioning of mitochondria PMID: 26673323
    5. KDM5 interacts with Foxo to modulate cellular levels of oxidative stress.KDM5 interacts with the lysine deacetylase HDAC4 to promote Foxo deacetylation, which affects Foxo DNA binding. PMID: 25329053
    6. dKDM5/LID regulates Drosophila hematopoietic development PMID: 26183107
    7. The results indicate that, at developmental genes, dKDM5/LID and ASH2 coordinately regulate H3K4me3 at the transcription-start site and that this dynamic regulation contributes to transcription. PMID: 22904080
    8. These findings highlight the importance of Lid function in the regulated removal and recognition of histone H3 lysine 4 during development. PMID: 21124823
    9. Lid knockdown using RNA interference results in a specific genome-wide increase in histone lysine methylation levels without affecting other patterns of H3 methylation, and results in an altered distribution of the chromo-helicase protein Chd1. PMID: 17351630
    10. Drosophila melanogaster protein 'little imaginal discs' (Lid), a JmjC domain-containing trithorax group protein, can demethylate histone H3trimethyl-Lys4. PMID: 17351631
    11. The finding that Lid antagonizes Rpd3 function provides an explanation for the genetic classification of Lid as a positive transcription regulator. PMID: 19114561

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    JARID1 histone demethylase family
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG9088

    STRING: 7227.FBpp0297914

    UniGene: Dm.2779



主站蜘蛛池模板： 天堂网www在线资源最新版| 精品多人p群无码| 欧美黑人又粗又大xxx| 日韩亚洲国产主播在线不卡| 久久婷婷成人综合色| 在线看片人成视频免费无遮挡 | 久久精品aⅴ无码中文字字幕| 日本一卡2卡3卡4卡无卡免费网站| 超清av在线播放不卡无码 | 特级毛片全部免费播放| 色综合伊人丁香五月桃花婷婷| 激情内射亚洲一区二区三区| 51国偷自产一区二区三区| 无码人妻一区二区三区精品视频| 国产精品高清不卡在线播放 | 日本丰满岳乱妇在线观看| 日本 精品 高清不卡| 国产人妖乱国产精品人妖| 香港三日本8a三级少妇三级99| 天天做天天爱天天综合网2021| 暖暖的在线观看日本社区| 国产果冻豆传媒麻婆| 日本熟妇乱人伦a片免费高清| 天堂а√在线最新版中文在线| 欧美人与禽猛交狂配| 2020精品国产午夜福利在线观看| 秋霞午夜一区二区三区黄瓜视频 | 亚洲国产品综合人成综合网站| 内射人妻少妇无码一本一道| 国精产品一区一区三区有限公司杨| a国产在线v的不卡视频| 人妻丝袜无码国产一区| 狠狠色噜噜狠狠狠狠五月婷| 欧美性猛交99久久久久99按摩| 18禁成年免费无码国产| 韩国19禁主播深夜福利视频| 少妇高潮大叫好爽| 90后极品粉嫩小泬20p| 国产成人精品.视频| 2018高清日本一道国产-在| 国产微拍精品一区二区|