在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Drosophila melanogaster Insulin-like receptor (InR), partial

  • 中文名稱(chēng):
    黑腹果蠅InR重組蛋白
  • 貨號(hào):
    CSB-YP357600DLU
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    黑腹果蠅InR重組蛋白
  • 貨號(hào):
    CSB-EP357600DLU
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    黑腹果蠅InR重組蛋白
  • 貨號(hào):
    CSB-EP357600DLU-B
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    黑腹果蠅InR重組蛋白
  • 貨號(hào):
    CSB-BP357600DLU
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    黑腹果蠅InR重組蛋白
  • 貨號(hào):
    CSB-MP357600DLU
  • 說(shuō)明書(shū):
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    InR
  • Uniprot No.:
  • 別名:
    InR; dinr; Dir-a; Inr-a; CG18402Insulin-like receptor; dIR; dInr; EC 2.7.10.1; dIRH) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta 1; Insulin-like receptor subunit beta 2]
  • 種屬:
    Drosophila melanogaster (Fruit fly)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Has a ligand-stimulated tyrosine-protein kinase activity. Required for cell survival. Regulates body size and organ size by altering cell number and cell size in a cell-autonomous manner. Involved in the development of the embryonic nervous system, and is necessary for axon guidance and targeting in the visual system. Also plays a role in life-span determination.
  • 基因功能參考文獻(xiàn):
    1. a sensory neuron-specific function of InR regulates the persistence of injury-associated hypersensitivity. PMID: 29752280
    2. Impairment of insulin signalling in the mushroom body neurons, a structure involved in associative learning, impairs feeding behaviour in the Drosophila larva.[Insulin] PMID: 22786647
    3. it was demonstrated that InR was expressed in follicular cells and that its expression in corpus allatum and follicular cells of Drosophila females was stage-specific, i.e., the expression intensity in young females greatly exceeded that in mature individuals. PMID: 29372799
    4. Results show that lifespan and behavioral senescence are independently regulated by the Drosophila insulin receptor. PMID: 26020640
    5. Study shows that the increase in the dopamine level in D. melanogaster females with the InR gene knockdown in corpus allatum ensures their increased resistance to starvation-induced stress PMID: 25937233
    6. results indicate that the Drosophila insulin-like peptide system is a crucial regulator of sleep PMID: 25581915
    7. This study has shown for the first time that suppression of InR expression in VNC leads to a rise in the survival of flies under conditions of toxic stress. PMID: 25966593
    8. The combined activities of Stit and InR in ectodermal epithelial tissues provide an RTK-mediated, two-tiered reaction threshold to varying nutritional conditions that promote epithelial organ growth even at low levels of InR signaling. PMID: 23935447
    9. InR, but not Tor, signaling non-autonomously promotes primordial germ cell differentiation. PMID: 24026119
    10. Mutations in the D. melanogaster Insulin Receptor (InR) alter SGP cell number but not ovarian morphogenesis PMID: 23022298
    11. controls growth and size by modulating PtdInsP(3) levels. PMID: 12163412
    12. required for photoreceptor-cell (R-cell) axons to find their way from the retina to the brain during development of the visual system; functions as a guidance receptor for the adapter protein Dock/Nck PMID: 12702880
    13. InR regulates cell growth and proliferation through the dP13K/dAkt pathway. PMID: 12893776
    14. Genetic manipulations in Drosophila melanogaster that impair the function of insulin-producing cells or of the insulin-receptor signaling pathway in the nervous system lead to increased sensitivity to the intoxicating effects of ethanol. PMID: 15592467
    15. insulin-like receptor pathway incorporates 4E-BP resistant cellular IRES containing mRNAs to functionally couple transcriptional activation with differential translational control in a cell that is otherwise translationally repressed by 4E-BP PMID: 17234883
    16. InR/Foxo signaling controls cell cycle progression by modulating dmyc expression and dMyc transcriptional activity PMID: 19211682
    17. In Drosophila melanogaster the level and pattern of variation at the 8-kb region of InR surveyed did not provide any indication of a recent selective event in this region. PMID: 19398492

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily
  • 組織特異性:
    Widely distributed throughout the embryo. Expressed at high levels in the embryonic nervous system. Larval expression is limited to the nervous system and all imaginal disks. Expressed at high levels in the adult nervous system and ovaries.
  • 數(shù)據(jù)庫(kù)鏈接:

    KEGG: dme:Dmel_CG18402

    STRING: 7227.FBpp0288669

    UniGene: Dm.1271



主站蜘蛛池模板: 成人午夜高潮免费视频在线观看| 私人毛片免费高清影视院| 日韩免费无码一区二区视频| 色综合久久久久综合99| 成人黄网站高清免费视频| 国产人妻精品午夜福利免费| 亚洲人成色7777在线观看| 日韩精品人妻无码久久影院| 日韩国产亚洲高清在线久草| 97人妻天天摸天天爽天天| 18禁裸乳无遮挡啪啪无码免费| av一区二区三区人妻少妇| 97夜夜澡人人双人人人喊| 欧美又粗又大xxxxbbbb疯狂| 国产午夜精品理论片| 97精品国自产在线偷拍| 中文精品久久久久鬼色| 少妇做爰免费视频了| 国产av激情久久无码天堂| 亚洲最大激情中文字幕| 中文字幕人成人乱码亚洲电影 | 色婷婷av99xx| 亚洲欧美韩国综合色| 俄罗斯少妇性xxxx另类| 免费观看美女裸体网站| 日本japanese丰满白浆| 国内精品久久久久影视| 99精品视频在线观看免费蜜桃| 超清av在线播放不卡无码| 欧美人牲口杂交在线播放免费| 国产肉丝袜视频在线观看| 国产精品成人av在线观看| 亚洲∧v久久久无码精品| 不卡无码人妻一区三区音频| 日本大香伊一区二区三区| 超清中文乱码字幕在线观看| 人人狠狠综合久久88成人| 色婷婷亚洲一区二区综合| 熟妇的味道hd中文字幕| 六月丁香综合在线视频| 欧美黑人激情性久久|