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  4. Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B (CycB), partial

Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B (CycB), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B(CycB) ,partial
  • 貨號：
    CSB-YP324935DLU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B(CycB) ,partial
  • 貨號：
    CSB-EP324935DLU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B(CycB) ,partial
  • 貨號：
    CSB-EP324935DLU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B(CycB) ,partial
  • 貨號：
    CSB-BP324935DLU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster G2/mitotic-specific cyclin-B(CycB) ,partial
  • 貨號：
    CSB-MP324935DLU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CycB
  • Uniprot No.：
  • 別名：
    CycB; CG3510G2/mitotic-specific cyclin-B
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Essential for the control of the cell cycle at the G2/M (mitosis) transition.
  • 基因功能參考文獻：
    1. During meiotic prophase in Drosophila males, transcript for the core cell cycle protein Cyclin B1 (CycB) is expressed in spermatocytes, but the protein does not accumulate in spermatocytes until just before the meiotic divisions. PMID: 26443637
    2. dFMRP and Caprin collaborate to control the cell cycle at the MBT by directly mediating the normal repression of maternal Cyclin B mRNA and the activation of zygotic fruhstart mRNA. PMID: 21068064
    3. induced by myb in eye imaginal disc PMID: 11847115
    4. Fzy/Cdc20 is responsible for catalyzing the first phase of cyclin B destruction that occurs on the mitotic spindle, whereas Fzr/Cdh1 is responsible for catalyzing the second phase of cyclin B destruction that occurs throughout the cell. PMID: 12082076
    5. interphase extension after cycle 10 is probably controlled by both cyclin B limitation and the DNA-replication checkpoint PMID: 14681192
    6. CycB is required for the division of germline stem cells and their precursors. PMID: 15723793
    7. We identified cyclin B as a direct transcriptional target of Fos in Drosophila melanogaster, with Fos binding to a region upstream of the cyclin B gene in vivo and cyclin B mRNA being specifically reduced under Fos loss-of-function conditions. PMID: 16966382
    8. A requirement of another Oskar-dependent factor in addition to Nanos is a mechanism for ensuring that Cyclin B regulation is strictly limited to the germline. PMID: 17360772
    9. Hsp90 is required to localize CycB to the mitotic spindle. PMID: 17376965

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  • 蛋白家族：
    Cyclin family, Cyclin AB subfamily
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG3510

    STRING: 7227.FBpp0071822

    UniGene: Dm.7295



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