在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Drosophila melanogaster F-box-like/WD repeat-containing protein ebi (ebi), partial

  • 中文名稱:
    Recombinant Drosophila melanogaster F-box-like/WD repeat-containing protein ebi (ebi), partial
  • 貨號:
    CSB-EP850198DLU1
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    ebi
  • Uniprot No.:
  • 種屬:
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    41.7 kDa
  • 表達(dá)區(qū)域:
    1-352aa
  • 氨基酸序列
    MSFSSDEVNFLVYRYLQESGFLHSAYVFGIESHISQSNINGALVPPAALLTILQKGLLYTEVEWSVGEDGEVARPIEGLSLIDAVMPEVKPLKPIVKTEPGKPGAVDSSAPAGGNQNNNAKPEIKIEPGTGVAGSAGGNKIAGSTTGTSTPTDQSASEVDSSGNAANNAGGTYAGNNGAGGNQASTGGSNSTSTPAGGDLAAPGASQKKSQNSNEAGSSSSGNAGNANATSTDDAASSTSTNGNSSTSSSVEQPTSGLTPAGGTVSTSNPDAAASGGASTATGSKAPSGAVTIRVGAQGNNVQSGSSNAQSSAPSGTISSSTSGGAGTPAALVPMDIDENIEIPESKARVLR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    F-box-like component of E3 ubiquitin ligase complexes; involved in R7 photoreceptor cell differentiation, cone cell development and neuronal cell cycle control. E3 ubiquitin ligase complexes mediate ubiquitination and subsequent proteasomal degradation of target proteins. Required for specification of R7 photoreceptor cell fate in the eye by participating in the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk), a general inhibitor of photoreceptor differentiation. Required to block the S phase entry in the peripheral nervous system and central nervous system in a process that does not involve the degradation of ttk. Involved in cone cell development by preventing the transcriptional repression mediated by Su(H) on Dl, probably by participating in a E3 complex that contains sno and mediates the ubiquitination and subsequent proteasomal degradation of some component of the Su(H) repressor complex.
  • 基因功能參考文獻(xiàn):
    1. Study proposes that the interplay of Crb expression in the DV boundary and ubiquitin-dependent Crb downregulation by Ebi provides a mechanism for the maintenance of Notch signaling during wing development. PMID: 27702784
    2. Results offer clear in vivo evidence that the Ebi-containing co-repressor complex acts in a distinct manner to regulate transcription that is required for modulating the output of various processes during Drosophila development. PMID: 26524764
    3. The antagonistic function of ebi against the Polycomb group silencing complex plays a role in the G1/S phase transition. PMID: 23919509
    4. EBI acts to activate (de-repress) transcription of Notch target genes important for Drosophila wing growth by functioning as a corepressor/coactivator exchange factor for SU(H). PMID: 22041576
    5. Ebi/AP-1 suppresses basal transcription levels of apoptotic genes and thereby protects sensory neurons from degeneration PMID: 22666340
    6. Ebi directly interacts with the Snail repressor and regulates Snail repressor function in the early embryo and in tissue culture cells. PMID: 18309295

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    WD repeat EBI family
  • 組織特異性:
    Widely expressed both in embryos and larvae.
  • 數(shù)據(jù)庫鏈接:

    KEGG: dme:Dmel_CG4063

    STRING: 7227.FBpp0077715

    UniGene: Dm.3639



主站蜘蛛池模板: 国产福利视频在线观看| 亚洲一区二区三区成人网站| 特级av毛片免费观看| 忘忧草社区中文字幕www| 影音先锋男人站| 久久久久蜜桃精品成人片| 日韩高清成片免费视频| 丰满又黄又爽少妇毛片 | 中出内射颜射骚妇| 九色porny丨国产首页注册| 久久久精品2020免费观看 | 欧美巨大xxxx做受中文字幕 | 免费毛片在线看片免费丝瓜视频| 天堂…中文在线最新版在线| 国产三级av在线播放| 亚洲精品日韩一区二区电影| 久久精品国产9久久综合| 亚洲欧美人高清精品a∨| 青青热久免费精品视频| 人妻中出受孕 中文字幕在线| 野狼av午夜福利在线| 中文字幕v亚洲ⅴv天堂| 又黄又粗又爽免费观看| 中文字幕在线不卡精品视频99| 精品人妻无码区二区三区| 99久热在线精品996热是什么| 国产亚洲精品美女久久久久| 人妻无码一区二区三区av| 日本免码va在线看免费| 精品人妻潮喷久久久又裸又黄| 国产精品成人无码免费| 小蜜被两老头吸奶头在线观看| 日韩理论午夜无码| 午夜三级a三级三点| 羞羞影院午夜男女爽爽| 精品久久久无码中文字幕 | 日本边添边摸边做边爱喷水| 亚洲日韩va在线视频| 国产精品 欧美 亚洲 制服| 国内最真实的xxxx人伦| 久久国产成人免费网站|