在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Drosophila melanogaster F-box-like/WD repeat-containing protein ebi (ebi), partial

  • 中文名稱:
    Recombinant Drosophila melanogaster F-box-like/WD repeat-containing protein ebi (ebi), partial
  • 貨號:
    CSB-EP850198DLU1
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    ebi
  • Uniprot No.:
  • 種屬:
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    41.7 kDa
  • 表達(dá)區(qū)域:
    1-352aa
  • 氨基酸序列
    MSFSSDEVNFLVYRYLQESGFLHSAYVFGIESHISQSNINGALVPPAALLTILQKGLLYTEVEWSVGEDGEVARPIEGLSLIDAVMPEVKPLKPIVKTEPGKPGAVDSSAPAGGNQNNNAKPEIKIEPGTGVAGSAGGNKIAGSTTGTSTPTDQSASEVDSSGNAANNAGGTYAGNNGAGGNQASTGGSNSTSTPAGGDLAAPGASQKKSQNSNEAGSSSSGNAGNANATSTDDAASSTSTNGNSSTSSSVEQPTSGLTPAGGTVSTSNPDAAASGGASTATGSKAPSGAVTIRVGAQGNNVQSGSSNAQSSAPSGTISSSTSGGAGTPAALVPMDIDENIEIPESKARVLR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    F-box-like component of E3 ubiquitin ligase complexes; involved in R7 photoreceptor cell differentiation, cone cell development and neuronal cell cycle control. E3 ubiquitin ligase complexes mediate ubiquitination and subsequent proteasomal degradation of target proteins. Required for specification of R7 photoreceptor cell fate in the eye by participating in the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk), a general inhibitor of photoreceptor differentiation. Required to block the S phase entry in the peripheral nervous system and central nervous system in a process that does not involve the degradation of ttk. Involved in cone cell development by preventing the transcriptional repression mediated by Su(H) on Dl, probably by participating in a E3 complex that contains sno and mediates the ubiquitination and subsequent proteasomal degradation of some component of the Su(H) repressor complex.
  • 基因功能參考文獻(xiàn):
    1. Study proposes that the interplay of Crb expression in the DV boundary and ubiquitin-dependent Crb downregulation by Ebi provides a mechanism for the maintenance of Notch signaling during wing development. PMID: 27702784
    2. Results offer clear in vivo evidence that the Ebi-containing co-repressor complex acts in a distinct manner to regulate transcription that is required for modulating the output of various processes during Drosophila development. PMID: 26524764
    3. The antagonistic function of ebi against the Polycomb group silencing complex plays a role in the G1/S phase transition. PMID: 23919509
    4. EBI acts to activate (de-repress) transcription of Notch target genes important for Drosophila wing growth by functioning as a corepressor/coactivator exchange factor for SU(H). PMID: 22041576
    5. Ebi/AP-1 suppresses basal transcription levels of apoptotic genes and thereby protects sensory neurons from degeneration PMID: 22666340
    6. Ebi directly interacts with the Snail repressor and regulates Snail repressor function in the early embryo and in tissue culture cells. PMID: 18309295

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    WD repeat EBI family
  • 組織特異性:
    Widely expressed both in embryos and larvae.
  • 數(shù)據(jù)庫鏈接:

    KEGG: dme:Dmel_CG4063

    STRING: 7227.FBpp0077715

    UniGene: Dm.3639



主站蜘蛛池模板: 西西人体大胆无码视频| 少妇熟女视频一区二区三区| 中文字幕乱码一区av久久| 久久和欧洲码一码二码三码| 亚洲色中文字幕无码av| 夜夜躁日日躁狠狠久久av| 亚洲精品午夜无码专区| 99热精品国自产拍天天拍| 色99久久久久高潮综合影院| 亚洲成av人片不卡无码| 精品久久久久久无码免费| 成人a大片在线观看| 大战丰满无码人妻50p| 国产男女猛烈无遮挡a片漫画| 欧美性猛交xxxx黑人| 久久久亚洲欧洲日产无码av| 福利姬国产精品一区在线| 成熟老妇女视频| 国产亚洲人成在线播放| 中文字幕有码无码人妻在线| 欧美无遮挡很黄裸交视频| 国精产品一区一区三区有限公司杨| 国产精品性夜天天拍拍2021| 精品亚洲卡一卡2卡三卡乱码| 人妻熟女一区二区aⅴ千叶宁真| 真人做人试看60分钟免费| 一本久久伊人热热精品中文字幕| 免费午夜福利不卡片在线播放| 好爽…又高潮了毛片免费看| 久久免费精品国产72精品| 少妇爱做高清免费视频| 亚洲精品成a人在线观看| 中文字幕无码不卡免费视频| 久久和欧洲码一码二码三码| 亚洲愉拍99热成人精品热久久| 免费午夜爽爽爽www视频十八禁 | 日本少妇高潮喷水免费可以看| 在线天堂资源www中文| 18禁高潮出水呻吟娇喘蜜芽| 久久超碰精品一夜七次郎| 亚洲午夜成人精品无码|