在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Drosophila melanogaster ETS-like protein pointed, isoform P2/D (pnt), partial

  • 中文名稱:
    黑腹果蠅pnt重組蛋白
  • 貨號:
    CSB-YP344687DLU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    黑腹果蠅pnt重組蛋白
  • 貨號:
    CSB-EP344687DLU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    黑腹果蠅pnt重組蛋白
  • 貨號:
    CSB-EP344687DLU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    黑腹果蠅pnt重組蛋白
  • 貨號:
    CSB-BP344687DLU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    黑腹果蠅pnt重組蛋白
  • 貨號:
    CSB-MP344687DLU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    pnt
  • Uniprot No.:
  • 別名:
    pnt; DMPOINT1A; ETS2; Ets58AB; pointed; CG17077; ETS-like protein pointed
  • 種屬:
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    ETS transcription factor with a prominent role during development of the eye and the nervous system. Required for glial-neuronal cell interactions at the ventral midline which are necessary for the proper elaboration of commissures in the embryonic CNS.; Required for normal EGFR-induced photoreceptor development probably as a downstream effector of Ras85D. In larval eye imaginal disks, activated by MAPK phosphorylation following EGFR activation, induces transcription of isoform P1 which in turn activates transcription of target genes essential for photoreceptor development.; Required for normal EGFR-induced photoreceptor development. Following transcriptional activation by isoform P2, acts as a constitutive activator of transcription, leading to induction of target genes essential for photoreceptor development. In larval brains, involved in the maintenance of type II neuroblast self-renewal and identity together with brat, btd and pros; prevents intermediate neuronal progenitor (INP) dedifferentiation by regulating the expression of erm probably via Notch signaling; suppresses Ase expression in type II neuroblasts and promotes the generation of intermediate neuronal progenitors.
  • 基因功能參考文獻:
    1. results demonstrate that PntP1 prevents both the premature differentiation and the dedifferentiation of INPs by regulating the expression of distinct target genes at different stages of imINP development. PMID: 27510969
    2. Both PntP1 and PntP2 are required for oenocyte specification. Since PntP1 is a downstream effector of EGF signaling, these findings provide insight into how a Hox factor can both trigger and potentiate the EGF signal to promote an essential cell fate along the body plan. PMID: 28715417
    3. PntP2 transcription factor plays a role in air sac development by regulation of the EGF ligand Vein protein. PMID: 26632449
    4. Specific disruption of either pntP1 or pntP2 resulted in the same R8-only phenotype, demonstrating that both Pnt isoforms are essential for photoreceptor recruitment PMID: 23757412
    5. Demonstrate that the Pointed-P2 PNT domain contains a dynamic N-terminal helix H0 appended to a core conserved five-helix bundle diagnostic of the SAM domain fold. PMID: 22936607
    6. The MAPK/ERK pathway acts via the ETS-1 transcription factor Pointed. This mechanism permits physiological adjustment of insulin sensitivity and subsequent maintenance of circulating glucose at appropriate levels. PMID: 22242005
    7. Pointed directly regulates the transcription of string and thereby cell proliferation PMID: 12447387
    8. In different types of glial cells, REPO can act alone, or cooperate with either TTK69 or PNTP1 to regulate different target genes. PMID: 12702656
    9. Data show that pannier acts upstream of pointed P2 in a developmental pathway in which pannier promotes cardiac mesoderm formation, and pointed acts subsequently to distinguish between cardioblast and pericardial cell fates. PMID: 12756183

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    ETS family
  • 數據庫鏈接:

    KEGG: dme:Dmel_CG17077

    STRING: 7227.FBpp0088658

    UniGene: Dm.2370



主站蜘蛛池模板: 末发育娇小性色xxxxx| 伊人蕉久中文字幕无码专区| 亚洲自偷自偷在线成人网址| 日产2021免费一区| 女女女女女裸体处开bbb| 香港三日本8a三级少妇三级99| 天天爱天天做天天爽夜夜揉| 乌克兰性欧美精品高清| 超碰97久久国产精品牛牛| 狼色精品人妻在线视频| 女人被狂爆到高潮免费视频| 日本一丰满一bbw| 日韩a∨精品日韩在线观看| 国产精品成人免费一区久久羞羞 | 日韩中文字幕在线一区二区三区 | 国产精品天干天干| 国产一区二区女内射| 久久精品av麻豆| 肉体裸交137日本大胆摄影| 中文亚洲欧美日韩无线码| 中文字幕日本最新乱码视频| 国产超碰人人模人人爽人人喊| 亚洲成av人片在线观看无| 日本高清在线一区二区三区| 高清不卡毛片免费观看| 国产成人av在线影院无毒| 国产人妻精品一区二区三区不卡| 久久久久久久久免费看无码| 77se77亚洲欧美在线| 免费网站看sm调教视频| 女人和拘做爰正片视频| 国产午夜精华无码网站| 国产精品专区免费观看软件| 波多野结衣av手机在线观看| 亚洲精品无码成人网站| 精品国产卡一卡2卡3卡| 18禁肉肉无遮挡无码网站| 欧美孕妇变态孕交粗暴| 国语少妇高潮对白在线| 亚洲人成影院在线观看 | 国产精品久久久久永久免费看|