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  4. Recombinant Drosophila melanogaster Dual specificity mitogen-activated protein kinase kinase dSOR1 (Dsor1)

Recombinant Drosophila melanogaster Dual specificity mitogen-activated protein kinase kinase dSOR1 (Dsor1)

  • 中文名稱：
    黑腹果蠅Dsor1重組蛋白
  • 貨號：
    CSB-YP634507DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Dsor1重組蛋白
  • 貨號：
    CSB-EP634507DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Dsor1重組蛋白
  • 貨號：
    CSB-EP634507DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Dsor1重組蛋白
  • 貨號：
    CSB-BP634507DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Dsor1重組蛋白
  • 貨號：
    CSB-MP634507DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Dsor1
  • Uniprot No.：
  • 別名：
    Dsor1; CG15793Dual specificity mitogen-activated protein kinase kinase dSOR1; Downstream of RAF; MAPKK; EC 2.7.12.2
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-396
  • 氨基酸序列
    MSKNKLNLVL PPVNTEATVA AATVAPTPPF KTPSGTDTHS LLGKPKTSID ALTETLEGLD MGDTERKRIK MFLSQKEKIG ELSDEDLEKL GELGSGNGGV VMKVRHTHTH LIMARKLIHL EVKPAIKKQI LRELKVLHEC NFPHIVGFYG AFYSDGEISI CMEYMDGGSL DLILKRAGRI PESILGRITL AVLKGLSYLR DNHAIIHRDV KPSNILVNSS GEIKICDFGV SGQLIDSMAN SFVGTRSYMS PERLQGTHYS VQSDIWSLGL SLVEMAIGMY PIPPPNTATL ESIFADNAEE SGQPTDEPRA MAIFELLDYI VNEPPPKLEH KIFSTEFKDF VDICLKKQPD ERADLKTLLS HPWIRKAELE EVDISGWVCK TMDLPPSTPK RNTSPN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Required downstream of Raf in the sevenless (sev), torso (tor), and Drosophila EGF receptor homolog (DER) signal transduction pathways. Involved in both positive regulation (at the posterior terminus) and negative regulation (at the anterior domain) of tll, as in other terminal class gene products, maybe via the ERK-A kinase.
  • 基因功能參考文獻：
    1. Ras-Dsor1 activity is independent of upstream activation by EGFR, and instead it appears to be activated by the insulin-like growth factor receptor to promote Wg signaling. PMID: 26542023
    2. the Ras/MEK/MAPK pathway regulates regional-fate specification via HSPGs during development PMID: 25848695
    3. Gem and Brm act antagonistically to modulate the EGFR-Ras-MAPK signaling pathway, by affecting Mek levels during Drosophila development PMID: 20416294
  • 蛋白家族：
    Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG15793

    STRING: 7227.FBpp0071248

    UniGene: Dm.2620



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