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  4. Recombinant Drosophila melanogaster Dorsal-ventral patterning protein Sog (sog), partial

Recombinant Drosophila melanogaster Dorsal-ventral patterning protein Sog (sog), partial

  • 中文名稱：
    黑腹果蠅sog重組蛋白
  • 貨號：
    CSB-YP637581DLU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅sog重組蛋白
  • 貨號：
    CSB-EP637581DLU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅sog重組蛋白
  • 貨號：
    CSB-EP637581DLU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅sog重組蛋白
  • 貨號：
    CSB-BP637581DLU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅sog重組蛋白
  • 貨號：
    CSB-MP637581DLU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    sog
  • Uniprot No.：
  • 別名：
    sog; CG9224; Dorsal-ventral patterning protein Sog; Short gastrulation protein
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Putative negative growth factor. Antagonist of dpp, a protein involved in patterning the dorsal region and in the development of the neuroectoderm; dpp inhibition is enhanced by tsg. Required for establishment of a narrow stripe of peak levels of BMP signaling in the dorsal midline of early embryos, that will give rise to the amnioserosa.
  • 基因功能參考文獻：
    1. These results suggest that synergistic interactions between Dl and Zld and between DI and Bcd are required for broad sog expression. PMID: 27528040
    2. This does not occur through cell-autonomous crosstalk between cGMP and BMP signal transduction, but likely through altered extracellular activity of Sog. PMID: 26440503
    3. Results suggest that integrins act by binding and possibly regulating the activity/availability of different forms of Sog during pupal development through an adhesion independent mechanism. PMID: 12835400
    4. Cysteine repeat domains and adjacent sequences determine distinct morphogenetic protein modulatory activities of sog. PMID: 15082551
    5. Sog and Cv promote BMP signaling by transporting a BMP heterodimer from the longitudinal veins into the crossvein regions. PMID: 15936330
    6. The effects of site-directed mutagenesis of tolloid protein on its' ability to cleave Sog protein are reported. PMID: 16488892
    7. sog acts during oogenesis to promote the formation of dorsal anterior structures of the eggshell and to establish the embryonic dorsal-ventral (DV) axis. PMID: 16781701

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  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type I membrane protein. Secreted.
  • 蛋白家族：
    Chordin family
  • 組織特異性：
    Abuts the dorsal dpp-expressing cells in a lateral stripe 14-16 cells wide. Later in embryogenesis it is expressed in neuroectoderm and in the endoderm spaced along the anterior-posterior axis of the developing gut.
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG9224

    STRING: 7227.FBpp0304150

    UniGene: Dm.3944



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