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  4. Recombinant Drosophila melanogaster Calpain-B (CalpB), partial

Recombinant Drosophila melanogaster Calpain-B (CalpB), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster Calpain-B(CalpB) ,partial
  • 貨號：
    CSB-YP894270DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Calpain-B(CalpB) ,partial
  • 貨號：
    CSB-EP894270DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Calpain-B(CalpB) ,partial
  • 貨號：
    CSB-EP894270DLU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Calpain-B(CalpB) ,partial
  • 貨號：
    CSB-BP894270DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Calpain-B(CalpB) ,partial
  • 貨號：
    CSB-MP894270DLU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CalpB
  • Uniprot No.：
  • 別名：
    CalpB; CG8107Calpain-B; EC 3.4.22.-; Calcium-activated neutral proteinase B; CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2]
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Calcium-regulated non-lysosomal thiol-protease.
  • 基因功能參考文獻(xiàn)：
    1. Autolytic activation, expression pattern and localization of calpain B. PMID: 14614768
    2. the acidic loop and the transducer region of calpain form an interconnected, extended structural unit that has the capacity to integrate and transduce Ca2+-evoked conformational changes over a long distance PMID: 14976200
    3. initial autolysis of Calpain B seems to occur intramolecularly, which supports the monomeric nature of Drosophila calpains PMID: 18032413
    4. CalpainB is required for AML1-ETO-induced blood cell disorders in Drosophila. PMID: 19581587
    5. the activation of the ERK pathway by extracellular signals results in the phosphorylation and activation of calpain B in fruit flies. PMID: 19694808

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  • 亞細(xì)胞定位：
    Cytoplasm. Membrane. Note=Translocates to intracellular membranes when calcium levels are increased.
  • 蛋白家族：
    Peptidase C2 family
  • 組織特異性：
    Strongly expressed in follicular and border cells of the oocyte. Ubiquitously expressed in early embryos. Localized to the trachea and their orifices, and to the larynx of late embryos. Restricted to the salivary gland in third instar larvae.
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG8107

    STRING: 7227.FBpp0076072

    UniGene: Dm.2874



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