在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Dog Potassium voltage-gated channel subfamily A member 2 (KCNA2), partial

  • 中文名稱:
    熟悉的犬KCNA2重組蛋白
  • 貨號(hào):
    CSB-YP638924DO1
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    熟悉的犬KCNA2重組蛋白
  • 貨號(hào):
    CSB-EP638924DO1
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    熟悉的犬KCNA2重組蛋白
  • 貨號(hào):
    CSB-EP638924DO1-B
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    熟悉的犬KCNA2重組蛋白
  • 貨號(hào):
    CSB-BP638924DO1
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    熟悉的犬KCNA2重組蛋白
  • 貨號(hào):
    CSB-MP638924DO1
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    KCNA2
  • Uniprot No.:
  • 別名:
    KCNA2; Potassium voltage-gated channel subfamily A member 2; CSMK1; Voltage-gated potassium channel subunit Kv1.2
  • 種屬:
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, KCNA6, KCNA7, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation of delayed rectifier potassium channels. In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member. Homotetrameric KCNA2 forms a delayed-rectifier potassium channel that opens in response to membrane depolarization, followed by slow spontaneous channel closure. In contrast, a heteromultimer formed by KCNA2 and KCNA4 shows rapid inactivation. Regulates neuronal excitability and plays a role as pacemaker in the regulation of neuronal action potentials. KCNA2-containing channels play a presynaptic role and prevent hyperexcitability and aberrant action potential firing. Response to toxins that are selective for KCNA2-containing potassium channels suggests that in Purkinje cells, dendritic subthreshold KCNA2-containing potassium channels prevent random spontaneous calcium spikes, suppressing dendritic hyperexcitability without hindering the generation of somatic action potentials, and thereby play an important role in motor coordination. Plays a role in the induction of long-term potentiation of neuron excitability in the CA3 layer of the hippocampus. May function as down-stream effector for G protein-coupled receptors and inhibit GABAergic inputs to basolateral amygdala neurons. May contribute to the regulation of neurotransmitter release, such as gamma-aminobutyric acid (GABA). Contributes to the regulation of the axonal release of the neurotransmitter dopamine. Reduced KCNA2 expression plays a role in the perception of neuropathic pain after peripheral nerve injury, but not acute pain. Plays a role in the regulation of the time spent in non-rapid eye movement (NREM) sleep.
  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein. Membrane. Cell projection, axon. Cell junction, synapse. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, synaptosome. Endoplasmic reticulum membrane. Cell projection, dendrite. Cell projection, lamellipodium membrane. Cell junction, paranodal septate junction.
  • 蛋白家族:
    Potassium channel family, A (Shaker) (TC 1.A.1.2) subfamily, Kv1.2/KCNA2 sub-subfamily
  • 組織特異性:
    Expressed in a wide variety of gastrointestinal smooth muscles. Not expressed in portal vein, renal artery, and uterus.
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 噜噜噜av久久| 无码人妻久久一区二区三区| 亚洲 欧美 成人 自拍 高清| 国产ktv交换配乱婬视频| 午夜福利av无码一区二区| 国产精品久久久久久久久免费| 国产婷婷一区二区三区| 麻豆丰满少妇chinese| 97免费人妻在线视频| 欧美成人无码a区视频在线观看| 99久久亚洲精品无码毛片| 天堂在线观看www| 欧美日韩不卡视频合集| 亚洲综合色在线观看一区| 激情综合丁香五月| 亚洲乱码中文字幕综合| 久久久久成人片免费观看r| 国产精品va在线观看老妇女| 无码国内精品久久人妻| 波多野结衣av无码| 亚洲真人无码永久在线| 国产在线高清亚洲精品二区| 久久综合伊人中文字幕| 欧美老熟妇牲交| 亚欧免费无码aⅴ在线观看蜜桃| 亚洲国产欧美在线成人app| 无码一区二区三区视频| 熟妇人妻久久中文字幕| 无码少妇一区二区三区浪潮av| 国产精品人妻一码二码| 成熟女人毛片www免费版在线| 天天躁日日躁狠狠躁2018| 中文字幕乱码一区二区免费| 亚洲狠狠婷婷综合久久久久图片| 五月婷婷俺也去开心| 狠狠色狠狠色综合网老熟女| 性色欲情网站iwww九文堂| 精品国产成人av在线| 性色欲情网站| 男女久久久国产一区二区三区| 欧美日韩亚洲国内综合网|