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  4. Recombinant Dog Platelet-derived growth factor subunit B (PDGFB)

Recombinant Dog Platelet-derived growth factor subunit B (PDGFB)

  • 中文名稱：
    熟悉的犬PDGFB重組蛋白
  • 貨號：
    CSB-YP754297DO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    熟悉的犬PDGFB重組蛋白
  • 貨號：
    CSB-EP754297DO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    熟悉的犬PDGFB重組蛋白
  • 貨號：
    CSB-EP754297DO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    熟悉的犬PDGFB重組蛋白
  • 貨號：
    CSB-BP754297DO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    熟悉的犬PDGFB重組蛋白
  • 貨號：
    CSB-MP754297DO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    PDGFB; Platelet-derived growth factor subunit B; PDGF subunit B; PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide
  • 種屬：
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    82-242
  • 氨基酸序列
    SLGSPTVAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPTFKKATV TLEDHLACKC ETVVAARPVT RTPGSSQDLR AAKTPQTRVT IRTVRVRRPP KGKHRKFKHT HDKKALKETL GA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.
  • 基因功能參考文獻：
    1. The aim of this study was to investigate the role of PDGF-A, PDGF-B, PDGFR-alpha and PDGFR-beta in canine lymphoma PMID: 25172054
    2. Ostectomy healing with or without platelet-rich plasma as indicated by radiography and expression of PDGF and TGF-beta expression are reported. PMID: 23111655
    3. In cutaneous hemangioma, 33.3% and 57.1% of cases were strongly and weakly positive, respectively, and 43.5% and 13.0% of hemangiosarcomas were strongly and weakly positive for PDGF-BB, respectively. PMID: 22419024
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    PDGF/VEGF growth factor family
  • 數據庫鏈接：


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