在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Dog Interferon gamma (IFNG)

In Stock
  • 中文名稱:
    Recombinant Dog Interferon gamma (IFNG)
  • 貨號:
    CSB-EP011050DO
  • 規格:
    ¥1536
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    IFN-gamma
  • 種屬:
    Canis lupus familiaris (Dog) (Canis familiaris)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    23.9 kDa
  • 表達區域:
    24-166aa
  • 氨基酸序列
    QAMFFKEIENLKEYFNASNPDVSDGGSLFVDILKKWREESDKTIIQSQIVSFYLKLFDNFKDNQIIQRSMDTIKEDMLGKFLNSSTSKREDFLKLIQIPVNDLQVQRKAINELIKVMNDLSPRSNLRKRKRSQNLFRGRRASK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits. In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading. Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference. Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL. Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation.
  • 基因功能參考文獻:
    1. IL-17A gene transcription level was positively correlated with mRNA expression for iNOS and IFN-gamma PMID: 26590047
    2. In dogs with leishmaniasis, there was high expression of interferon gamma in lymph nodes. PMID: 21511273
    3. These findings suggest that polyunsaturated fatty acids are able to influence proliferation of peripheral blood mononuclear cells in healthy and atopic dogs but do not seem to influence cytokine transcription. PMID: 20187917
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Type II (or gamma) interferon family
  • 組織特異性:
    Released primarily from activated T lymphocytes.
  • 數據庫鏈接:


主站蜘蛛池模板: 77se77亚洲欧美在线| 长腿校花无力呻吟娇喘| s级爆乳玩具酱国产vip皮裤| 99r在线精品视频在线播放| 国产乱码二卡3卡四卡| 久久久久99精品成人片直播| 亚洲熟妇色xxxxx亚洲| 亚洲欧美日韩综合一区在线| 久久亚洲国产精品五月天婷| 欧美放荡的少妇| 香港三级精品三级在线专区| 成人精品一区日本无码网站| 国产精品亚洲а∨怡红院| 色哟哟精品视频在线观看| 亚洲日韩成人无码| 人妻丝袜av先锋影音先| 少妇无码精油按摩专区| 国产亚洲欧美在线专区| 国产精品无码一区二区在线| 国产视频亚洲精品视频| 无码日韩做暖暖大全免费不卡| 五月丁香六月综合缴清无码| 夜夜爽狠狠天天婷婷五月| 日本熟妇美熟bbw| 熟妇无码乱子成人精品| 欧美一区二区日韩国产| 日韩av毛片无码免费| 337p日本欧洲亚洲大胆69影院| 白天躁晚上躁麻豆视频| 日韩 国产 变态另类 欧美| 人妻少妇无码专视频在线| 国产精品一区二区久久国产| 夜夜爱夜夜做夜夜爽| 少妇人妻挤奶水中文视频毛片| 免费人成在线观看网站| 久久久www成人免费毛片| 中国少妇初尝黑人巨高清 | 亚洲国产成人va在线观看天堂 | 又黄又爽又色的视频| 亚洲成在人网站无码天堂| 国产内射老熟女aaaa|