在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Dog Baculoviral IAP repeat-containing protein 5 (BIRC5)

Recombinant Dog Baculoviral IAP repeat-containing protein 5 (BIRC5)

  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-YP814170DO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-EP814170DO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-EP814170DO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-BP814170DO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-MP814170DO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    BIRC5Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor survivin
  • 種屬：
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-142
  • 氨基酸序列
    MGASSLPPAW QLYLKDHRVS TFKNWPFLEG CACTPDRMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLSE FLKLDKERAK NKIAKETNNK QKEFEETAKK VRCAIEQLAA AE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7. Essential for the maintenance of mitochondrial integrity and function.
  • 基因功能參考文獻：
    1. The results indicate that survivin is commonly expressed in canine lymphomas and that survivin does not exhibit anti-apoptotic activity in canine lymphomas. PMID: 28865215
    2. These findings strongly suggest that survivin-directed therapies might be effective in treatment of canine lymphoma and osteoporosis and support evaluation of EZN-3042 in dogs with cancer. PMID: 24923332
    3. These findings suggest that survivin could play an important role in the maintenance of the hair follicle cycle as well as in tumour initiation and maintenance of cancer stem cells. PMID: 24800266
    4. The level of survivin expression increased with increasing malignancy, designating survivin as a new diagnostic marker in the assessment of malignancy of sebaceous tumours. PMID: 22681570
    5. Survivin overexpression is associated with tumor malignancy in dog. PMID: 16243724
    6. Malignant proliferation in canine hemangiosarcomas is associated with bcl-2 and survivin expression. PMID: 18479697
    7. Survivin expression is a negative prognostic factor that can predict early treatment failure of dogs that present with stage IIIa or IVa, B-cell LSA when treated with a CHOP-based protocol. PMID: 18647159
    8. Nuclear survivin was detected in transitional cell carcinoma and cystitic tissues but not in normal urinary bladder tissues. PMID: 18672973
    9. This study demonstrated survivin expression in normal canine epidermis; nuclear survivin expression in pre-neoplastic and neoplastic lesions demonstrated a possible association of survivin with development of squamous cell carcinomas in humans and dogs. PMID: 20178473

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Midbody.
  • 蛋白家族：
    IAP family
  • 數據庫鏈接：


主站蜘蛛池模板： 欧美精品一区二区精品久久| 国产精品卡一卡二卡三| 人妻熟人中文字幕一区二区| 日韩 国产 变态另类 欧美| 最新的国产成人精品2022| 动漫av纯肉无码免费播放| 亚洲精品久久久av无码专区| 国产精品无码av一区二区三区| 亚洲精品乱码久久久久久蜜桃| 狠狠狠狼鲁亚洲综合网| 亚洲va综合va国产产va中文| 69堂人成无码免费视频果冻传媒| 国产欧美va天堂在线观看视频| h肉动漫无码无修6080动漫网| 国产精品99久久免费| 亚洲桃色天堂网| 色妞www精品视频| 中出人妻中文字幕无码| 刺激性视频黄页| 精品aⅴ一区二区三区| 乱色国内精品视频在线| 日韩欧群交p片内射中文| 免费人成视频x8x8入口| 久久久久青草线综合超碰| 色偷偷尼玛图亚洲综合| 67pao国产成视频永久免费| 麻豆国产一区二区三区四区| а√天堂www在线天堂小说| 亚洲成年网站青青草原| 国产午夜不卡片免费视频| 国产3p露脸普通话对白| 九九热在线视频观看这里只有精品 | 欧美孕妇乳喷奶水在线观看| 免费一区二区三区成人免费视频| 国产av天堂亚洲国产av下载| 无码视频一区二区三区在线观看| 国产又大又粗又爽的毛片| 久久亚洲中文字幕精品一区| 四虎国产精品永久地址49| 久久久久人妻精品一区三寸蜜桃| 亚洲gv猛男gv无码男同|