在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Dog Baculoviral IAP repeat-containing protein 5 (BIRC5)

Recombinant Dog Baculoviral IAP repeat-containing protein 5 (BIRC5)

  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-YP814170DO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-EP814170DO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-EP814170DO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-BP814170DO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Dog Baculoviral IAP repeat-containing protein 5(BIRC5)
  • 貨號：
    CSB-MP814170DO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    BIRC5Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor survivin
  • 種屬：
    Canis familiaris (Dog) (Canis lupus familiaris)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-142
  • 氨基酸序列
    MGASSLPPAW QLYLKDHRVS TFKNWPFLEG CACTPDRMAE AGFIHCPTEN EPDLAQCFFC FKELEGWEPD DDPIEEHKKH SSGCAFLSVK KQFEELTLSE FLKLDKERAK NKIAKETNNK QKEFEETAKK VRCAIEQLAA AE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7. Essential for the maintenance of mitochondrial integrity and function.
  • 基因功能參考文獻：
    1. The results indicate that survivin is commonly expressed in canine lymphomas and that survivin does not exhibit anti-apoptotic activity in canine lymphomas. PMID: 28865215
    2. These findings strongly suggest that survivin-directed therapies might be effective in treatment of canine lymphoma and osteoporosis and support evaluation of EZN-3042 in dogs with cancer. PMID: 24923332
    3. These findings suggest that survivin could play an important role in the maintenance of the hair follicle cycle as well as in tumour initiation and maintenance of cancer stem cells. PMID: 24800266
    4. The level of survivin expression increased with increasing malignancy, designating survivin as a new diagnostic marker in the assessment of malignancy of sebaceous tumours. PMID: 22681570
    5. Survivin overexpression is associated with tumor malignancy in dog. PMID: 16243724
    6. Malignant proliferation in canine hemangiosarcomas is associated with bcl-2 and survivin expression. PMID: 18479697
    7. Survivin expression is a negative prognostic factor that can predict early treatment failure of dogs that present with stage IIIa or IVa, B-cell LSA when treated with a CHOP-based protocol. PMID: 18647159
    8. Nuclear survivin was detected in transitional cell carcinoma and cystitic tissues but not in normal urinary bladder tissues. PMID: 18672973
    9. This study demonstrated survivin expression in normal canine epidermis; nuclear survivin expression in pre-neoplastic and neoplastic lesions demonstrated a possible association of survivin with development of squamous cell carcinomas in humans and dogs. PMID: 20178473

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Midbody.
  • 蛋白家族：
    IAP family
  • 數據庫鏈接：


主站蜘蛛池模板： 人人妻一区二区三区| 激情人妻另类人妻伦| а天堂8中文最新版在线官网| 日韩一区二区三区精品| 国产一区二区怡红院| 国产成人无码av大片大片在线观看| 国产萌白酱喷水视频在线观看| 性生交大片免费看女人按摩 | 无码av永久免费专区麻豆| 国产亚洲精品久久久久久久| 亚洲精品午夜无码专区| 国产日产亚洲系列最新美使用方法 | 无码人妻斩一区二区三区| 国产a∨精品一区二区三区不卡 | 99久久精品日本一区二区免费| 做爰高潮视频免费的看| 久久久无码精品国产一区| 老色69久久九九精品高潮| 欧美国产国产综合视频| 亚洲综合另类小说色区| 亚洲成av人影院无码不卡| 国产精品一卡二卡三卡四卡| 亚洲熟妇无码八av在线播放| 337p西西人体大胆瓣开下部| 国产丰满乱子伦无码专区| 鲁鲁网亚洲站内射污| 人妻无码久久精品人妻| 18禁无码永久免费无限制网站| 精品无码久久久久国产电影| 国语自产精品视频在线看 | 成人性生交大片免费看小说| 十八禁啪啪无遮挡网站| 小嫩妇好紧好爽18禁视频| 亚洲日韩中文字幕一区| 欧美成 人版中文字幕| 国产精品香蕉视频在线| 亚洲精品天堂成人片av在线播放 | 毛片免费视频肛交颜射免费视频| a国产在线v的不卡视频| 免费观看男女性高视频| 国产又粗又大又黄|