在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Dengue virus type 2 Genome polyprotein, partial

  • 中文名稱:
    Recombinant Dengue virus type 2 Genome polyprotein,partial
  • 貨號:
    CSB-YP322433DCH
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Dengue virus type 2 Genome polyprotein,partial
  • 貨號:
    CSB-EP322433DCH
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Dengue virus type 2 Genome polyprotein,partial
  • 貨號:
    CSB-EP322433DCH-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Dengue virus type 2 Genome polyprotein,partial
  • 貨號:
    CSB-BP322433DCH
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Dengue virus type 2 Genome polyprotein,partial
  • 貨號:
    CSB-MP322433DCH
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    Genome polyprotein [Cleaved into: Protein prM; Peptide pr; Small envelope protein M; Matrix protein); Envelope protein E; Non-structural protein 1; NS1)]; Fragment
  • 種屬:
    Dengue virus type 2 (strain Thailand/PUO-218/1980) (DENV-2)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Prevents premature fusion activity of envelope proteins in trans-Golgi by binding to envelope protein E at pH6.0. After virion release in extracellular space, gets dissociated from E dimers.; Acts as a chaperone for envelope protein E during intracellular virion assembly by masking and inactivating envelope protein E fusion peptide. prM is the only viral peptide matured by host furin in the trans-Golgi network probably to avoid catastrophic activation of the viral fusion activity in acidic Golgi compartment prior to virion release. prM-E cleavage is inefficient, and many virions are only partially matured. These uncleaved prM would play a role in immune evasion.; May play a role in virus budding. Exerts cytotoxic effects by activating a mitochondrial apoptotic pathway through M ectodomain. May display a viroporin activity.; Binds to host cell surface receptor and mediates fusion between viral and cellular membranes. Envelope protein is synthesized in the endoplasmic reticulum in the form of heterodimer with protein prM. They play a role in virion budding in the ER, and the newly formed immature particle is covered with 60 spikes composed of heterodimer between precursor prM and envelope protein E. The virion is transported to the Golgi apparatus where the low pH causes dissociation of PrM-E heterodimers and formation of E homodimers. prM-E cleavage is inefficient, and many virions are only partially matured. These uncleaved prM would play a role in immune evasion.; Involved in immune evasion, pathogenesis and viral replication. Once cleaved off the polyprotein, is targeted to three destinations: the viral replication cycle, the plasma membrane and the extracellular compartment. Essential for viral replication. Required for formation of the replication complex and recruitment of other non-structural proteins to the ER-derived membrane structures. Excreted as a hexameric lipoparticle that plays a role against host immune response. Antagonizing the complement function. Binds to the host macrophages and dendritic cells. Inhibits signal transduction originating from Toll-like receptor 3 (TLR3).; Disrupts the host endothelial glycocalyx layer of host pulmonary microvascular endothelial cells, inducing degradation of sialic acid and shedding of heparan sulfate proteoglycans. NS1 induces expression of sialidases, heparanase, and activates cathepsin L, which activates heparanase via enzymatic cleavage. These effects are probably linked to the endothelial hyperpermeability observed in severe dengue disease.
  • 亞細胞定位:
    [Peptide pr]: Secreted.; [Small envelope protein M]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein.; [Envelope protein E]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein.; [Non-structural protein 1]: Secreted. Host endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.


主站蜘蛛池模板: 免费无码av片在线观看国产| 无码免费毛片手机在线无卡顿| 性xxxx欧美老妇胖老太269| 无码中文字幕人妻在线一区 | 国产精品久久国产三级国不卡顿| 亚洲乱码中文字幕久久孕妇黑人| 日日橹狠狠爱欧美视频| 亚洲第一狼人伊人av| 亚洲第一成人网站| 日本人妻人人人澡人人爽| 午夜伦4480yy私人影院久久| 国产成人小说视频在线观看| 国模无码视频一区二区三区| 亚洲偷自拍国综合| 亚洲а∨天堂久久精品| 国产一在线精品一区在线观看| 国产精品久久毛片av大全日韩| 日产日韩亚洲欧美综合下载| 亚洲日本乱码一区二区产线一∨| 自拍偷自拍亚洲精品播放 | 内射囯产旡码丰满少妇| 久久久一本精品99久久精品66| 亚洲人禽杂交av片久久| 亚洲精品久久婷婷丁香51| 艳妇乳肉豪妇荡乳xxx| 亚洲色大网站www永久网站| 欧美人与动牲交免费观看网| 少妇粉嫩小泬白浆流出| 欧美牲交a欧美牲交aⅴ图片| 动漫成人无码精品一区二区三区| 欧洲熟妇色xxxx欧美老妇软件| 国产一区二区女内射| 亚洲 日本 欧美 中文字幕| 久久不见久久见www电影免费| 国产成人精品优优av| 国产精品人妻久久毛片| 艳妇乳肉豪妇荡乳在线观看| 久久伊人蜜桃av一区二区| 日本三级手机在线播放线观看 | 中文字幕日韩人妻无码| 丰满少妇被猛烈进入高清播放|