在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Delphinapterus leucas Cellular tumor antigen p53 (TP53)

  • 中文名稱:
    Recombinant Delphinapterus leucas Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-YP840473DJB
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Delphinapterus leucas Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-EP840473DJB
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Delphinapterus leucas Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-EP840473DJB-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Delphinapterus leucas Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-BP840473DJB
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Delphinapterus leucas Cellular tumor antigen p53(TP53)
  • 貨號:
    CSB-MP840473DJB
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    TP53; P53; Cellular tumor antigen p53; Tumor suppressor p53
  • 種屬:
    Delphinapterus leucas (Beluga whale)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-387
  • 氨基酸序列
    MEESQAELGV EPPLSQETFS DLWKLLPENN LLSSELSPAV DDLLLSPEDV ANWLDERPDE APQMPEPPAP AAPTPAAPAP ATSWPLSSFV PSQKTYPGSY GFHLGFLHSG TAKSVTCTYS PALNKLFCQL AKTCPVQLWV SSPPPPGTRV RAMAIYKKSE YMTEVVRRCP HHERCSDYSD GLAPPQHLIR VEGNLRAEYL DDRNTFRHSV VVPYEPPEVG SDCTTIHYNF MCNSSCMGGM NRRPILTIIT LEDSNGNLLG RNSFEVRVCA CPGRDRRTEE ENFHKKGQSC PELPTGSAKR ALPTGTSSSP PQKKKPLDGE YFTLQIRGRE RFEMFRELNE ALELKDAQAG KEPGESRAHS SHLKSKKGQS PSRHKKLMFK REGPDSD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2. However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2.
  • 相關疾病:
    p53 is found in increased amounts in a wide variety of transformed cells. p53 is frequently mutated or inactivated in many types of cancer.
  • 亞細胞定位:
    Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族:
    P53 family


主站蜘蛛池模板: 国产精品人妻一区夜夜爱| 中文在线www天堂网| 青青草原综合久久大伊人精品 | 亚洲一区 日韩精品 中文字幕 | 艳妇乳肉豪妇荡乳av| 成人区精品一区二区婷婷| 四虎亚洲精品高清在线观看| 9lporm自拍视频区| 无码人妻丝袜在线视频| 国产精品久久久久久久9999| 日本无码人妻精品一区二区蜜桃 | 亚洲熟女久久色| 欧美国产日韩a欧美在线观看| 日日噜狠狠噜天天噜av| 亚洲日韩中文字幕一区| 国产精品无码日韩欧| 隔壁人妻被水电工征服| 日韩一区二区三区高清电影| 一区二区三区人妻无码| 色婷婷综合和线在线| 永久黄网站色视频免费看| 一道久久爱综合久久爱| 亚洲人成小说网站色在线| 中文亚洲无线码49vv| 色欲网天天无码av| 欧美又大粗又爽又黄大片视频| 免费无码a片一区二三区| 夜晚成人18禁区导航网站| 少妇被躁爽到高潮无码人狍大战 | 国产黑色丝袜视频在线观看网红| 国产人妻久久精品二区三区老狼| 亚洲妇熟xxxx妇色黄| 亚洲欧洲日产韩国在线看片| 中文字幕亚洲综合久久青草| 久久丫精品久久丫| 夜色福利院在线观看免费| 天天摸夜夜摸夜夜狠狠添| 久久精品www人人爽人人| 好吊妞无缓冲视频观看| 亚洲孰妇无码av在线播放| 国精产品一区一区三区|