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  4. Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA (ddrA)

Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA (ddrA)

  • 中文名稱：
    Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA(ddrA)
  • 貨號：
    CSB-YP865774DJA
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA(ddrA)
  • 貨號：
    CSB-EP865774DJA
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA(ddrA)
  • 貨號：
    CSB-EP865774DJA-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA(ddrA)
  • 貨號：
    CSB-BP865774DJA
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Deinococcus radiodurans Single-stranded DNA-binding protein DdrA(ddrA)
  • 貨號：
    CSB-MP865774DJA
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ddrA
  • Uniprot No.：
  • 別名：
    ddrA; DR_0423Single-stranded DNA-binding protein DdrA; DNA damage response protein A
  • 種屬：
    Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-208
  • 氨基酸序列
    MKLSDVQKRL QAPFPAHTVS WKPAAFNAER TRALLLAHVD ARAVQDRLDA VCPDDWSFEM EVVSGAEVPT VKGRLTVLGV TREDIGEAPE GSMAAYKAAA SDAMKRCAVQ FGIGRYLYDL PKQWADWDDA RRGPKHLPEL PEWARPDHER TPGGAHLVQA MEQLRYELPE DLDLQREVYK HLKAALGSIH PVPTGPVPTN PVQGGRAA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    ssDNA-binding protein that contributes to the ionizing radiation resistance of D.radiodurans. Plays a role in DNA repair and genome reconstitution, in a RecA-independent process, since DdrA is essential for recovery from severe genomic fragmentation as a result of exposure to severe levels of ionizing radiation in an environment lacking nutrients. In vitro, binds to the 3'-ends of single-stranded DNA, protecting them from nuclease degradation. Thus, DdrA is part of a DNA end-protection system that helps to preserve genome integrity following irradiation or desiccation. Does not display DNA strand annealing activity, unlike eukaryotic Rad52 protein homologs.
  • 基因功能參考文獻：
    1. the DR0423 protein is the DNA damage response A protein PMID: 15361932
  • 蛋白家族：
    RAD52 family
  • 數據庫鏈接：

    KEGG: dra:DR_0423

    STRING: 243230.DR_0423



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