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Recombinant Danio rerio Sphingosine 1-phosphate receptor 1 (s1pr1), partial

  • 中文名稱:
    斑馬魚s1pr1重組蛋白
  • 貨號:
    CSB-YP875293DIL1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    斑馬魚s1pr1重組蛋白
  • 貨號:
    CSB-EP875293DIL1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    斑馬魚s1pr1重組蛋白
  • 貨號:
    CSB-EP875293DIL1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    斑馬魚s1pr1重組蛋白
  • 貨號:
    CSB-BP875293DIL1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    斑馬魚s1pr1重組蛋白
  • 貨號:
    CSB-MP875293DIL1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    s1pr1; edg1; Sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P1; Sphingosine 1-phosphate receptor Edg-1; S1P receptor Edg-1
  • 種屬:
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate.
  • 基因功能參考文獻:
    1. Wnt/beta-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling in the process of neovascularization of the central nervous system and blood-brain barrier formation. PMID: 30451830
    2. Individual s1prs showed unique expression patterns with some overlapping expression domains during early embryogenesis. PMID: 26094551
    3. Sphingosine 1-phosphate receptor signaling regulates proper embryonic vascular patterning PMID: 23229546
    4. Report role for S1PR1 in regulation venous endothelial barrier function. PMID: 22837470
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數據庫鏈接:


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