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  4. Recombinant Danio rerio RNA-binding protein 24 (rbm24)

Recombinant Danio rerio RNA-binding protein 24 (rbm24)

  • 中文名稱：
    斑馬魚rbm24重組蛋白
  • 貨號：
    CSB-YP745088DIL
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    斑馬魚rbm24重組蛋白
  • 貨號：
    CSB-EP745088DIL
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    斑馬魚rbm24重組蛋白
  • 貨號：
    CSB-EP745088DIL-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    斑馬魚rbm24重組蛋白
  • 貨號：
    CSB-BP745088DIL
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    斑馬魚rbm24重組蛋白
  • 貨號：
    CSB-MP745088DIL
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    rbm24
  • Uniprot No.：
  • 別名：
    rbm24; RNA-binding protein 24; RNA-binding motif protein 24; RNA-binding protein SEB-4
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-230
  • 氨基酸序列
    MHTTQKDTTY TKIFVGGLPY HTTDSSLRKY FEVFGEIEEA VVITDRQTGK SRGYGFVTMA DRSAADRACK DPNPIIDGRK ANVNLAYLGA KPRVMQPGFT FGVPQIHPAF IQRPYGIPTH YVYPQAFMQP SVVIPHIQPT ATSATASSPY IDYTGAAYAQ YASAATAAAA AAYEQYPYAA SPAATGYVAA AGYGYAMQQP LATAAPGSAA AAAAAFGQYQ PQQLQAERMQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes. Plays a role in the regulation of mRNA stability and mRNA translation to which it is bound. Involved in myogenic differentiation by regulating myog levels. Binds to a huge amount of mRNAs. Required for embryonic heart development, sarcomer and M-band formation in striated muscles.
  • 基因功能參考文獻：
    1. Both Rbm24a and Rbm24b are also required for normal somite and craniofacial development. PMID: 25170925
    2. Rbm24 involving in the regulation of cardiac gene expression, sarcomeric assembly, and cardiac contractility. PMID: 22345307
    3. rbm24a is a key developmental cardiac genes with unequal roles in cardiovascular formation PMID: 22011202
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 數據庫鏈接：


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