在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Danio rerio Protein naked cuticle homolog 1 (nkd1)

Recombinant Danio rerio Protein naked cuticle homolog 1 (nkd1)

  • 中文名稱：
    斑馬魚nkd1重組蛋白
  • 貨號：
    CSB-YP648794DIL
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    斑馬魚nkd1重組蛋白
  • 貨號：
    CSB-EP648794DIL
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    斑馬魚nkd1重組蛋白
  • 貨號：
    CSB-EP648794DIL-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    斑馬魚nkd1重組蛋白
  • 貨號：
    CSB-BP648794DIL
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    斑馬魚nkd1重組蛋白
  • 貨號：
    CSB-MP648794DIL
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    nkd1; Protein naked cuticle homolog 1; Naked-1
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-440
  • 氨基酸序列
    GKLHSKHAA ICKARESPEG DSFVVNACLA RKGLDDWMVK QKYYCSSSRV DQRDCQQKNN CELSPRDPLD EGYAEGISDE HYRLEVALPP EKTDSCSVEE RMQGTEGSAT VGPHKQLQFE ELECAVSVEE DNRQEWTFTL YDFDNNGKVT REDITSLLHT IYEVVDASVN HSPSSSKTLR VKLSVAPDSS QRWKNCTQTN TDTPNPKHKG EKCIEDSKTS EKKSRAFLRR YHAEHHSQQG CQRHCVDENL ERRNHYLDLA GIENYTSRFG TAAPATEPAK PTHATRSSNQ SRSRSQEPEN GQVHPAHHRR SQTMSTDPPA ILTRHTHALR SPKTHRTPPT QASAGRVMRR GAPPPPSVPN QTPPHQSSGP YRRHKQRPKE ALHYRALGPS VTSGPVLEKE HVRDLPSLVL YEGGLAQVVQ RHEHHHHHEH HHHYHHFYQS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
  • 基因功能參考文獻：
    1. This work reveals that the zebrafish Nkd1 EF-hand is essential to balance Wnt signaling inputs and modulate the appropriate outputs, while the Drosophila-like EF-Hand primarily functions in beta-catenin signaling. PMID: 29180104
    2. Nkd1 activity is specifically dependent on Wnt ligand activation of the receptor. Nkd1 is recruited to the Wnt signalosome with Dvl2, where it becomes activated to move into the cytoplasm to interact with beta-catenin, inhibiting its nuclear accumulation. PMID: 25904337
    3. Nkd1 functions as a passive antagonist of Wnt signaling, functioning only when homeostatic levels of Wnt signaling have been breached or when Wnt signaling becomes destabilized. PMID: 24009776
    4. Data demonstrate that Nkd1 binds to beta-catenin and prevents its nuclear accumulation. Nkd1 function is dependent on its interaction with the cell membrane. PMID: 21490931
    5. Nkd1 knockdown in the dorsal forerunner cells causes beta-catenin nuclear localization/transcriptional activation & changes in DFC migration, Kupffer's vesicle formation, ciliogenesis, left-right patterning, & asymmetric charon expression. PMID: 20858476
    6. data indicate that zebrafish Nkd1 and Nkd2 function to limit both canonical and non-canonical Wnt signaling PMID: 17689523

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane. Cytoplasm.
  • 蛋白家族：
    NKD family
  • 數據庫鏈接：


主站蜘蛛池模板： 99精品国产成人一区二区 | 国产熟妇乱xxxxx大屁股网| 乱子伦一区二区三区| 欧美高清性色生活片免费观看| 亚洲国产成av人天堂无码| 国产精品99久久久久久宅男小说 | 强 暴 疼 哭 处 女 身子视频| 久久久久高潮综合影院| 欧美一区二区日韩国产| 婷婷色爱区综合五月激情 | 欧美性xxxxx极品少妇直播| 看曰本女人大战黑人视频| 国产人成网线在线播放va | 99久久99久久免费精品蜜桃| 日本成aⅴ人片日本伦| 免费女人裸体视频无遮挡免费网站| 国产高清一区二区三区直播| 777亚洲精品乱码久久久久久| 亚洲乱亚洲乱妇小说网| 中文天堂最新版在线www| 久久99久久99久久综合| 欧美极品少妇×xxxbbb| 疯狂做受xxxx高潮不断| 日韩午夜理论免费tv影院| 鲁鲁狠狠狠7777一区二区| 国产免费内射又粗又爽密桃视频 | 无码人妻一区二区三区av| 精品人妻码一区二区三区| 伊人久久久av老熟妇色| av无码av不卡一区二区| 熟妇与小伙子matur老熟妇e| 色妞精品av一区二区三区| 亚洲欧美在线制服丝袜国产| 成人性做爰aaa片免费| 国产av国片偷人妻麻豆| 天天躁久久躁日日躁| 人人人妻人人人妻人人人| 玩弄japan白嫩少妇hd| 草草影院精品一区二区三区| 无码中文字幕乱在线观看| 亚洲熟悉妇女xxx妇女av|