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  4. Recombinant Danio rerio Homeobox protein orthopedia B (otpb)

Recombinant Danio rerio Homeobox protein orthopedia B (otpb)

  • 中文名稱：
    斑馬魚otpb重組蛋白
  • 貨號：
    CSB-YP732227DIL
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    斑馬魚otpb重組蛋白
  • 貨號：
    CSB-EP732227DIL
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    斑馬魚otpb重組蛋白
  • 貨號：
    CSB-EP732227DIL-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    斑馬魚otpb重組蛋白
  • 貨號：
    CSB-BP732227DIL
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    斑馬魚otpb重組蛋白
  • 貨號：
    CSB-MP732227DIL
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    otpb
  • Uniprot No.：
  • 別名：
    otpb; otp; otp1; otpa; Homeobox protein orthopedia B
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-315
  • 氨基酸序列
    MLSHADLLDT RLGMKDAAAE LLVHREALKC RLGGTDSGHP GDLTSATETV EGTTLLPGEE ISNGGSNPNG MQQVNAKDQE KQQQQNSNQT GGQQNQQKQK RHRTRFTPAQ LNELERSFAK THYPDIFMRE ELALRIGLTE SRVQVWFQNR RAKWKKRKKT TNVFRAPGTL LPTHGLPQFP SAAAAAMGDS LCSFHANDTR WAAAGMPGVS QLQIPPSLGR QQAMAQSLSQ CSLGAGPPPN NMGLSGSLSS NGSGLQSHLY QPTFPGMVPA SLSGPTNVTG SPQLCSSPDS DMWRGTSIAS LRRKALEHTV SMSFT
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in the specification of isotocin cells. Required for the specification of dopaminergic neurons in the developing hypothalamus and posterior tuberculum.
  • 基因功能參考文獻：
    1. These findings reveal a new role for Otp in controlling developmental neuropeptide balance in a discrete oxytocinergic hypothalamic circuit whose disrupted development affects social behavior. PMID: 28094761
    2. Identification of an evolutionarily conserved vertebrate OTP enhancer module with activity in a restricted area of the forebrain. PMID: 25427861
    3. These observations suggest that the requirement for otpa and otpb function during development of the larval diencephalon is partially redundant. PMID: 24073233
    4. Otp1 transcription factor is important for regulation of diencephalon development and early neuronal progenitors. PMID: 17074092
    5. Orthopedia is one of the few known transcription factors that can determine aspects of the dopaminergic phenotype and the first known factor to control the development of the diencephalospinal dopaminergic system. PMID: 17481897
    6. Results describe the ontogeny of vasotocin-expressing cells in zebrafish, and the selective requirement for the transcriptional regulators orthopedia and single-minded 1 in the preoptic area. PMID: 18330923

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Paired homeobox family, Bicoid subfamily
  • 組織特異性：
    Isoform 1 and isoform 2 are expressed in brain and testis.
  • 數據庫鏈接：

    KEGG: dre:30316

    STRING: 7955.ENSDARP00000122985

    UniGene: Dr.81295



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